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I'm about to start cymbalta but I'm currently on gabapentin an oxcarbazepine but I can't quite oxcarbazepine with out hurting really bad I was thinking about taking all three an then discontinue oxcarbazepine any suggestions

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    Have you discussed this with your GP or specialist? The three drugs are quite different in how they work, but my advice would be to discuss it with your doc(s) or even a pharmacist.

    If you choose to start the Cymbalta and continue with the Gabapentin (which I assume it is intended to replace) then the safest thing to do would perhaps be to gradually reduce the Gabapentin whilst gradually increasing the Cymbalta dose. The problem with drugs of this type is that stopping them suddenly can lead to all manner of withdrawal issues, and similarly starting them at a high dose, equivalent to the dose of the Gabapentin you are currently taking, is likely to increase the risk of side effects. The other problem is that these types of drugs used for neuropathic pain take a while to reach effective levels in your blood, sometimes as long as 6-12 weeks.To be honest I really think you need speak to a doctor or pharmacist to get the best advice.

    On the plus side Cymbalta has been shown to be extremely effective in combatting neuropathic pain.

    Good luck.

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      Cymbalta is also known as Duloxetine, it is one of the newer generation of antidepressants. And as with all other antidepressants it can be used to combat neuropathic pain. Studies have shown it to be extremely effective in Fibromyalgia. Incidentally Fibromyalgia research has demonstrated the condition to be due to a 'signal failure' in the neurotransmitter/receptors of the either the Brain or affected muscles, or even both! The sufferer perceives too much or too severe a pain as a result of the 'signal failure'. It acts on the neurotransmitters of the brain and quells the impulses ergo less pain.

      As with all drugs there are side effects, too many to list!

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