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Dapsone and Pancreatitis?

Posted , 6 users are following.

mar94072
mar94072

Hi everyone. I was recently hospitalized for acute pancreatitis. After going through many tests, my doctor said that the medication Dapsone is probably what caused the inflammation of the pancreas. Has anyone ever experienced or heard of this? I honestly hope it's not true because Dapsone is the only medication that has given me some relief from LS. Thanks.

0 likes, 8 replies

8 Replies

  • christine97462
    christine97462 mar94072

    Posted

    I'm unfamiliar with dapsone. Is it topical, or oral? I'm sorry you are going through this; pancreatitis is so painful!

    • Guest
      Guest christine97462

      Posted

      Dapsone is an oral anti-inflammatory with anti-infective properties. It is given for a wide range of conditions including many types of skin disorders, Hansens disease, dermatitis, and leprosy. You can't take it for a long time.

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  • SnappyCat
    SnappyCat mar94072

    Posted

    I had never heard of dapsone until your letter. Looks like it is an immunosuppressant.

    Do you use it topically? Or orally?

    There are other similar meds you could try, topically, that work on the same logic, suppress the immune reaction. I use both steroids and tacrolimus. Because it is such a tiny amount, used topically, I'd be surprised to have other reactions like pancreatitis.

  • mar94072
    mar94072

    Posted

    i take it orally. I also use steroid ointment as needed before Dapsone my doctor prescribed Protopic cream but that didnt help at all

    • SnappyCat
      SnappyCat mar94072

      Posted

      Wow...I'm surprised. I'm certainly not a medical professional, but I'm surprised than anyone would give you an oral immunosuppressant for LS. LS is such a localized disease and there is no reason, that I understand, to suppress the entire immune system for your whole body. Seems risky to me. I'd be inclined to believe the doc who said that it might have been the cause for your pancreatitis. In fact, I'd worry about what else might crop up.

      As for the protopic and steroids...

      1. Protopic isn't a near-term "relief" type of med. You put it on, and you may have some side effects or you may not feel anything at all. It won't relieve your discomfort today. If you expected it to give you relief from your symptoms immediately, it just wouldn't do that.
      2. It takes months for protopic to help treat the LS. Maybe it didn't work for you. Don't know. But, if you didn't stick with it for a good long period, I don't think you'd see any benefit.
      3. You say you used steroid ointment, "as needed"...but what I understand the protocol to be is to use the steroid every day until your symptoms dissipate. Then taper down to 2x a week ...pretty much for life. Even using protopic, I still use the steroid 2x a week...maybe get to 1x a week soon.

      The steroid is the gold standard for LS. If you were on clob and had trouble with it, there are lots and lots of different varieties of steroids to try.

      All this makes me wonder...what kind of a doc are you seeing? I, personally, suggest that you might consider a dermatologist. LS is a disease of the skin...dermatologists are doctors of the skin...that's my take.

    • mar94072
      mar94072 SnappyCat

      Posted

      Thank you for all of this information.

      you are correct that i used Protopic for immediate relief and stopped when I didn't. And clobetadol is my go-to for flareups but I haven't usef it regularly.

      My doctor is a dermotologist. I suppose I have trusted het because she was the doctor who diagnosed me with LS after many many years of misdiagnoses by various gynocologists. I will make an appointment with her to discuss this.

    • SnappyCat
      SnappyCat mar94072

      Posted

      Absolutely right strategy!Let us know how you make out! 😃

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