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I am so desperate for help. I've been sick for more than fifteen years now & have been searching to try & find out what its wrong with me so much so that I finally had a genetic Thyroid test done privately. It came back with various results most of which were ok but there were 3 red flags that came up as follows:-
COMT - Very slow clearance of stress hormones & oestrogen. You may be at increased risk of thyroid dysfunction when under stress & due to poor elimination of oestrogen.
TNF-a - The (A) result increases likelihoood of an over-reactive inflammatory immune response. This means you are at risk of chronic inflammatory & autoimmune conditions including Hashimoto's thyroiditis or Graves disease.
TRHR - The (A) result has been found to be more common in people with Graves disease & is linked to the presence of the thyroid stimulating hormone receptor antibodies (TRAb), associated with increased risk of developing GD.
I have many symptoms including: - Swollen neck, Jaw pain, heat intolerance, hand tremors, feeling of heart beating very fast, constant peeing, sore gritty eyes with pain behind the eyes. I have also had, low Vit B, still have low Vit D, Stage 3 kidney disease,
high plasma glucose & itching skin to name a few. My problem is that my blood tests come withing the ranges for thyroid most of the time. I have had gone over the T4 range a few times though, but my TSH has been 0.59 ti 1,2. This is why none of the medical professionals i've seen take the fact that I have these symptoms seriously.
I would also add that I have an older sister who has the disease. Please can someone out there help me I feel so deperately ill all the time & don't now who to turn to. Should I try to see an endocrinologist? I would be so grateful for any help you can give me.
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