diarrhea and nausea following complete knee replacement

Posted , 8 users are following.

On May 7, I had a knee replacement.  The first 2 weeks, I took Percocet (Oxycontin) and then switched to Tylenol 3.  I suffered with diarrhea and nausea and quit taking the pain medication .  Finally, my symptoms have lessened.  Has anyone else also suffered with intestinal problems?

1 like, 9 replies

9 Replies

  • Posted

    I had horrible nausea and constipation with any of the pain pills they gave me.  The nausea was so bad I stopped taking any pain medication also...thankfully I wasn't in that much pain after the 3 week.  I asked my surgeon how do people get hooked on this!!!  He said that in some people's brain the drug is interrupted as a poison so the body wants to get rid of it.  

  • Edited

    Hi Ed!

    My body's reaction to Oxycodone and Hydrocodone as well as Tramadol is NOT GOOD!😫😨😰

    Poor pain management was not the worst thing with the above medications. I experienced nausea, flu symptoms without fever, dizziness, constipation and real loopiness. I got off the Oxycodone within two weeks (first TKR) and the same time frame with the Hydrocodone and my second TKR three months later. I took Tramadol twice with my second TKR and that was ENOUGH! I was giving myself the blood thinner shots the first two weeks and couldn't take anything like aspirin or Ibuprofen. After the two weeks were over I took my Ibuprofen and felt SO, SO,SO much better! My main issue was the swelling, and the Ibuprofen, being an anti-inflammatory, REALLY helped with the swelling!

    I also put my compression stockings back on, iced, and walked around every hour inside the house those first few weeks.

    It took about a month to eliminate all the anesthesia, medication and additional toxins from my body. My poor body didn't know what hit it and reacted in all kinds of ways to those drugs! My nurse at the hospital encouraged me to drink PLENTY of ice water which I did in the hospital and continued once I came home.

    I'm happy to hear that your symptoms have lessened! ?? Know that you have PLENTY of company when it comes to having weird reactions to medications! After all, Everytime we take any medication or eat any food or drink any substance, our body chemistry changes. Surgery of any kind is a trauma to the body. It takes awhile to overcome all that takes place following surgery.

    Wishing you much success in your recovery!??🤗

    (TKRs June and October 2015)

    • Posted

      Thanks for your response.  I had an abdominal CT scan and several additional tests including blood and stool analysis.  I'm schedules to see a GI specialist in July but I believe that this is related to the pain medications following surgery. The physical therapists tell me my range of motion is at 110 degrees and I need to get to 120 degrees

    • Posted

      We are right at the same level!  I’m at 110 right now as well!  Keep up the good work!  (I’m trying to stay positive too!). Hope all goes well with your GI visit!  Let us know how it goes!
  • Posted

    I can not take any narcotics without severe vomiting that last for hours. I’ve tried everything.  For my TKR on April 30 after leaving the hospital, I took Tylenol & Ibuprofen ( although I am on a blood thinner)...& made sure I was icing my knee frequently.  This treatment for pain was not great & it has been difficult, but it is better than suffering for hours with the severe intestinal problems.  Finally the pain is more tolerable now.

    Wishing you well!

  • Posted

    Percocet is oxycodone plus Tylenol.  T-3's are straight codeine plus Tylenol.  Your doc could have tried hydrocodone plus Tylenol (Vicodin, Norco) but it's also codeine-based so you might have had the same reaction.  Some patients are prescribed straight-up morphine or even hydromorphone (Dilaudid) for very, very serious pain when the codeine-related opioids don't provide relief.  You could try some Tramadol (Ultram) at this point as it's a very mild opioid used as a transitional med before going down to plain OTC ibuprofen or Tylenol.

    Yeah...some people have bad reactions to opioids. We don't hear a lot of it on the Forum as constipation from hydrocodone is the most common side effect reported.  Most of the time, when someone has a bad reaction to a med, it tends to be fairly quickly and the patient is switched to a different med immediately. 

  • Posted

    This is common with these pain killers I didn’t get it but many people do, they usually make you constipated , and can make you vomit especially when doses are increased as in cancer patients , but many people are affected even at low doses 
  • Posted

    I have had a rough time with nausea and cramping and off again on again diarrhea. I think the 2 weeks of antibiotics I was put on coupled with Celebrex and the Opioids really just did me in. I'm 5 weeks out from a total knee replacement, and I really wish I had been prepared for all the other things that go along with it.

  • Posted

    im seven weeks out of a total knee replacement and have nausea . been off pain killers since first week but was taking anti inflammatory until last week.

    ive had alot of surgeries over the years but this one has been my hardest recovery.

    no energy and stomach problems.

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