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Disturbed sleep on Venlafaxine and Mirtazapine

Posted , 3 users are following.

Ala1483
Ala1483

I have been on Mirtazapine 30 and Venlafaxine together for 6 weeks now. My Venlafaxine got increased to 225 a week ago and I have been having horrendous sleep for the past few days. I sleep max 4hours and I feel exhausted during the day which is not helping my depression. Has anyone on similar combo has been struggling with sleep? Does it pass? 

0 likes, 9 replies

9 Replies

  • pixie22
    pixie22 Ala1483

    Posted

    When i had disturbed sleep when first taking this combination i assumed it was due to the depression and it did improve as the medications started working and the depression lifted. I do still get vivid dreams but i don't worry about them. I hope this reassures you.

    • pixie22
      pixie22 Ala1483

      Posted

      Yes, i've been stable on this combo (225mg ven and 30mg mirt) for 7 years and able to get on with my life.

    • Ala1483
      Ala1483 pixie22

      Posted

      You are giving me hope! I will try to switch Ven to am to see whether it helps with sleep. I have to give it time... 
  • jacqueline66035
    jacqueline66035 Ala1483

    Posted

    High Ala. Haven't had these in combination but have used both on their own. The mirt help with sleep but for me the venlafaxine disrupted my sleep. What type of ven are you on? If it's the XR version it's best to take it in the morning so as to minimise the disruption to sleep. It can take time to find a combination/dosage to suit everyone. I have been on ven since beginning of July (wrongly prescribed as later had to have dose lowered for Bipolar 2 diagnosis). Tried quetiapine for 4 and a half weeks and was then changed to Abilify which is helping alot more. If you are struggling with your sleep don't be afraid to ask your doctor if there are alternatives that could help you. All the best for a speedy recovery.

    • Ala1483
      Ala1483 jacqueline66035

      Posted

      I have been taking my Ven XR in the evening so will switch to am to see whether it helps with sleep. 
    • Ala1483
      Ala1483 jacqueline66035

      Posted

      Thanks Jackie, I slept a bit better but still kept waking up. I have had an unbearable headache all day... I increased to 225 a week ago. I hope it goes away by tomorrow. X
    • jacqueline66035
      jacqueline66035 Ala1483

      Posted

      Hi Ala. Glad your sleep was a little better. It's so frustrating not getting any sleep. Hope your headache eases soon too. Always takes a wee while to settle into a new dose. Fingers crossed for you to get an even better nights sleep tonite. I have a whole arsenal of things to help my sleep: lavender spray, rescue remedy drops, chamomile tea, white noise app on my phone and the metal Indian head message thing you can buy off Amazon! . Maybe you've tried all these already. If not maybe they could help? Good luck. Xx

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