Does anyone use Desmopressin to release norturia?

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A friend of mine has started taking desmopressin to help with how many times he has to get up during the night to void. According to him, he went from 5 times a night to once a night in just a week. Desmopressin is used by children to prevent bed wetting. I'll be seeing my Uro tomorrow and will let you all know what he thinks...maybe drug interactions?

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    This is not a new drug for nocturia. It has been used for quite some time to help reduce the amount of urine produced at night. My understanding is that desmopressin helps to reduce the amount of urine produced while sleeping. However, it does not reduce the total amount of urine produced in a 24 hour period. Therefore, you will urinate more liquid during the daytime. I tend to produce a lot of urine at night as well, but have not yet tried desmopressin. I find that compression socks worn during the daytime (not at night while sleeping) helps to reduce the amount of liquid that pools in my legs during the daytime. Consequently, when the body is horizontal at night, there is less liquid that needs to be processed by the kidneys. I expect that desmopressin is more effective, but if you haven't tried compression socks, maybe you should try them first. Also, I want to mention that I have no signs of swollen legs or ankles, yet my journal clearly shows that compression socks do help to reduce the amount of liquid I urinate during the nighttime. On average, this reduced the number of times I get up by 1 to around 2 to 3 times a night.

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    Hi harry1289,

    I was prescribed a desmopressin analogue called Noqdirna when I was 67. It was a tablet that dissolved under the tongue (oral lyophilisate) but unfortunately it didn't work for me. I took it for three weeks but had to stop taking it because I put on over 4Kg due to water retention. I also had to have my sodium levels monitored because of my age as hyponatremia is a possible side-effect. It's not something I would like to go back to.


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