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Does Mirtazapine have withdrawal symptoms?

Posted , 6 users are following.

pixie22
pixie22

My psychiatrist has just agreed that I can try reducing my antidepressant medication. I'm on 225mg venlafaxine and 30mg mirtazapine, and he's suggested I gradually reduce the mirtazapine first, and see what happens He's warned me that i might notice less sedation, so sleep less well. Are there any other withdrawal symptoms I should know about? Anyone else tried it?

0 likes, 9 replies

9 Replies

  • julie1111
    julie1111 pixie22

    Posted

    Hi well done coming off ADs i do know mirtz is more seditive the lower the dose.. i weaned my self off mirtz last year, i experienced a rise in engry also very vivid dreams, hope this helps, goodluck hun
    • james-manc-uk
      james-manc-uk julie1111

      Posted

      Hi when I moved on to venlafaxine people said I was a changed person! But I still want to come off them completely, I know i'm the real me!!
  • gen07717
    gen07717 pixie22

    Posted

    Hi Pixie, congratulations, that's great news for you.  You may want to post the question in the Mirtazapine group as you'll probably get a better response on there.  I hope the reduction goes well.  Mirtazapine is well known for having greater sedation at lower does so it shouldn't affect your sleep until you come right off it, if indeed it does.  Good luck xxx
  • maureen45116
    maureen45116 pixie22

    Posted

    Be very careful when you begin withdrawing from the venlafaxine.  There are many dangerous side effects of withdrawal.  Rage, crying jags, utter despair, virulent insomnia, night sweats, tremors, confusion ... the list goes on.  But you can do it.  It takes courage to gut it out but you can get this poison out of your system.
    • pixie22
      pixie22 maureen45116

      Posted

      Yes I have heard it's difficult to reduce venlafaxine. Psychiatrist has suggested gradually coming off mirtazapine then waiting 6 months before trying any other changes.
  • pixie22
    pixie22

    Posted

    Thanks for the replies. It's encouraging to know it can be done. Coming off venlafaxine will be a bigger problem, but that's a long time in the future.
  • james-manc-uk
    james-manc-uk pixie22

    Posted

    I didn't have any major problems coming off it. But I was on Venlafaxine after
  • stephen25089
    stephen25089 pixie22

    Posted

    Hi I'm total opposite coming off vf now on mirtazapine .this is my 5th day with no vf don't know really why  I'm changing from one horrible drug to another and I'm thinking what is the point is it really worth it ,I know thing it's a long slog ,do you know what mirtazapine does,and can you tell me how did it help you .
    • pixie22
      pixie22 stephen25089

      Posted

      According to my psychiatrist, mirtazapine has more of a sedative action than venlafaxine, and fewer withdrawal symptoms. He did warn that many of the withdrawal symptoms people report could actually be the depression and anxiety coming back. All these drugs take several weeks to get into your system and start working. It's a hard painful slog in the meantime, though. You have to hope the doctor knows what he/she is talking about!
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