Does Pred lose its potency over time?

Posted , 11 users are following.

It's just that I have some 5 mg tablets with an expiry date of July 2018, and am wondering if they will still be OK to take? It's my own fault as I haven't been careful about taking them in sequence.

0 likes, 7 replies

7 Replies

  • Posted

    Steroids do lose strength over time but, being only a few months past the "official" expiration date, I would expect the loss to be minimal.

  • Posted

    I found myself in the same position because the surgery had given me 5s instead of 1s and I hadn't realised until I had taken them home from the pharmacy. By the time I got round to using them they were out of date and they definitely had lost strength. You may find they do not give the same response to the pain but may be worth a try though I wouldn't continue if you feel they are not working. I ended getting a new lot.

  • Posted

    Officially the powers that be will say it isn't OK - in fact for solid medications like pred, up to about 6 months is perfectly OK according to pharmacologists. They don't self-destruct overnight obviously but may deteriorate if the conditions they are being kept in are wrong as that makes a difference too. I can't imagine that barely 4 months will make much if any difference - I would try them.

    • Posted

      Thanks Eileen, that's good to know. I've recently upped my dose as I have been having shoulder pain, but after I started another packet which turned out to be out of date the pain came back, so it did occur to me it might be due to those pills not being so strong. I've gone on to a more recent packet and I'll see if it makes a difference. I do like to have a stock in my cupboard in case there comes a point when I can't get them on prescription, so I've been sort of hoarding them, but with no regard to the dates. Better system needed!

    • Posted

      I actually had a problem with new tablets once - I'd been fine on enteric coated for ages and then got a load dispensed in a bottle rather than in blister packs so there was no expiry date. Within a few days of starting them I flared - but it was only with the 5mg pills, the new 2.5mg ones were fine but obviously I got through them rather fast! I came to the conclusion it was from a different manufacturer and the fillers in the pills were different. If you are noticing a difference then don't use them, they aren't that expensive anyway.

  • Posted

    Steroids should last a few months after their sell by date provided you have kept them in a dark place away from sunlight. I have that problem occassionally.

    • Posted

      My tablets are in a covered box in a dark cupboard but, unfortunately, due to a mistake at the GP surgery they were well out of date. When I cut them to use as 2.5s they didn't have the desired effect on the pain. I had been so careful about not over ordering and used them in sequence so that they wouldn't be out of date. Ah well. the best laid plans.........

Report or request deletion

Thanks for your help!

We want the community to be a useful resource for our users but it is important to remember that the community are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the community is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.