Dose needing adjusting after changing tonight time regime

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Hello Have been hypothyroid since around 1998 and am now nearly 70 years of age.  After reading a lot over the years about taking levothyroxine at night instead of the morning I decided after speaking to my gp to give it a go.  I have been taking it at night for around 2 months.  My question is anyone who has changed from morning to night found they have needed a change in the dose they take.  Thanks.

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  • Posted

    Hi, my circumstances are similar. I changed to last thing at night a year or so ago and did not notice any difference.
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  • Posted

    When I was first diagnosed, about 6 years ago..  the levothyroxine gave me bad side effects.  So until my body was able to adjust to the levo, I started taking half my dose in the morning and the other half at night.  It worked great for a while and I had no side effects at all from the levo. My TSH levels stayed stable also.  After 4 years doing half in the morning and half at night, my TSH levels started to slowly raise higher and higher.  I decided to start taking my full dose in the morning, now that my body was used to it, and my TSH levels went back down to the optimal TSH level of 1.00.  I figured out that I was getting careless with eating too close to my night dose.  I am a night snacker and it was interferring with the amount of levo my body was absorbing.  Anyway..  I would say that I have benifited greatly by taking half of my dose at night, but if you like snacking at night and cannot refrain from eating for 4 hours before your night dose, then I would say it's better to take the levo in the morning, or you may find that you will keep needing a dose adjustment..

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    • Posted

      Thanks for your reply.  I changed from the morning because I now have to take other tablets and fibredrink 3mins before I eat breakfast so it would make it hard to take the thyroxine in the morning as I would have to take ages before the fibre which would count as food.  At night as I rarely go to bed before midnight I can take it then having not eaten for around 3 hours.  I will check with my gp though as some toime and get her to check my levels.  Earlier this year I suffered from some palpitations and chest discomfort on walking and gp could not decide if it was my asthma playing up or heart trouble.  Heart scans were clear so it was assumed asthma however during this period I had routine blood tests and it was found that my tsh was too low so my dose was lowered from 125mcg to 100mcg and the symptoms went away.  I have noticed a bit again and although it might be to do anxiety over other problems I won't go into I thought that maybe as I was taking the thyroxine at night well away from food it was possible being assorbed better and that the dose needed lowering again hence my original post.  Time will tell.  Hope all goes well for you.  

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