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I took my first 15mg yesterday just before bed and am still groggy now!

Tomorrow there is somewhere just have to do and want to enjoy it too, I dont understand it but there seems to be a consensus that 30mg will not give as many side effects, should I try that tonight or what should I do.

Not liking the effects of this allready,although some sleep was welcomed last night. smile

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  • Posted


    I am on a very low dose of Mirtrazapine - only 7.5mg because I react to drugs. I feel a bit drowsy still after 2 weeks and in fact now feel drowsier than I did at the start so am wondering whether you tried the higher dose and if it did help with the grogginess? Like you I am grateful for the sleep but I would like to be awake during the day. I dont quite understand why a higher dose would mean less groggy!! Jill

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  • Posted

    The'groginess' does improve after a few weeks and there is some evidence that the higher doses of mirtazapine have less of a sedative effect. This is something to do with the serotonin uptake transmitters in the brain. I shall be looking at this effect closely as I hope to increase mirtazapine and I would hate to have to rely on sleeping pills again. Mirtazapine does seem to knock people out for the first few weeks so you should think very carefully about driving until you know how the drug affects you.
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    Thanks Pooh Bear - it helps to manage the side effects if you have some idea about why and for how long! I increased the dose to 15mg last night and dont feel more groggy today which I sort of expected. We shall see what happens. I have noticed that I am very sensitive to medications so in fact I am surprised I dont have any of the other side effects other people are experiencing! Jill
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  • Posted

    I'm on 45mg and the sedative effects of this med were much greater at a lower dose. I don't feel groggy on a morning any more...hmm, but then i don't sleep so well either. Hope the groggy feeling wears off for you soon smile
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