Doses of PPIs and H2 antagonists

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I've just moved to a new area and the GP is horrified by the doses of lansoprazole and ranitidine I am prescribed. I take 60mg lansoprazole twice a day and 450 mg ranitidine daily in divided doses.

Do others consider this excessive? A gastro-enterologist prescribed them. I've tried taking less but my symptoms are not controlled.

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9 Replies

  • Posted

    whats the alternative? They always yell at the dosage, but what else can one do when they don't get relief?

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    • Posted

      That's the problem. I wouldn't wish this amount of reflux on anyone. Well, maybe on my GP, then she can feel it for herself.

      What dose are you on, Gilda?

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  • Posted

    I'm not fat to begin with, so I went on the alkaline diet, watching everything I eat, lost 20 lbs. On Tectra only once a day, but on Motilium. I find the motilium helps. I take 2 before breakfast and 2 before supper. Then I take Zantac befored bed. No s**t food, no pop, no fried stuff, trying to eat very little at one time. Take a probiotic, and metamucil. Try to walk after I eat and don't eat after 7 - or 6 p.m.

    Trying to sleep sitting up. Trying not to bend over or bend down. Even an operation is only 50% success and there could be more problems afterwards. If this doesn't work, I will try another type of pill. ppi are the worst for you - it will cause problems down the road, and getting off will be extremely hard, (for you especially) will take you maybe a year of weaning yourself off. I really wanted to try to find natural ways instead of ppi, but caved in. I am not sure it is really helping me.Try to drink lots of water....trying everything and hoping for a remission!

     

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    • Posted

      Thanks so much for all that, Gilda. it's given me loads to think about.

      What are the problems with PPIs?

      I'm having the surgery, but not for several months.

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  • Posted

    If you have surgery you should be off all drugs hopefully!

    Ppi can deplete magnesium and vitamin b 12

    Get a blood test to see

    If you research ppi you will see only for short term at the lowest dosage but most people stay on forever and many for years - 

    Sorry u need surgery - but I hope you have good surgeon as when done properly there has been good success 

    Keep in touch and best of luck 

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    • Posted

      Thanks, Gilda. I have just had a blood test for magnesium levels but not B12.

      Thanks you for your help.

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  • Posted

    How long have you been on lansoprazole 60mg 2 times a day for? Did you notice any side effects during that period, how old are you why are you taking taking them exactly?
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    • Posted

      Hi Eric,

      I have been on this awful dose for two years, and they were prescribed for extreme reflux. I am now 61. The side-effects have been a lowered white cell count, low magnesium. I have had a few infections which \i might not have had if my white cells weren't occasionally knocked out. I'm waiting for an operation on the hiatus hernia.

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  • Posted

    Whatever you do - if the time comes - DO not quit cold turkey

    You will need expert help and guidance to slowly wean yourself off!! It could take several months 

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