Doses with Sinclair Method

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On the weekends, I may typically drink at brunch and then not again until the evening. With the Sinclair Method, do I only take the pill once in the morning??

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  • Posted

    Hi Amanda,

    You should, of course, discuss dosage with your doctor but from what many doctors have told us, they are confident that each naltrexone tablet provides full coverage for between 10 and 12 hours (which can vary on individual circumstances).

    So, if you take a tablet at 8am for brunch, then doctors tell us that it will fully protect you until around 6-8pm.  If any drinking happens beyond that point, then they tell us that another tablet should be taken one hour before the first drink of the evening.

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  • Posted

    As far as I know with both Naltrexone and Nalmefene you must take the pill one hour prior to drinking if you are using Naltrexone, and two hours prior to drinking if you are using Nalmefene.  I also think that either pill covers you for a period of about 10 hours approx.  So if you were to drink after 9 or 10 hours of taking the pill, your medication would not be 100% effective and a redose (then wait the appropriate time) would be needed.  Do your own research into this, but this is my understanding.
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