Doxazosin Stress incontinence - Ladies only!

Posted , 11 users are following.

I'm a middle aged woman. I've been on beta-blockers for over 30 years. Three of years ago, I was prescribed doxazosin in addition to atenolol. Originally I was prescribed 4mg taken last thing at night of the slow release form and had little trouble with it. However my GP changed this to 2mg of a generic standard doxazosin. I began to feel very 'hung-over' and thick headed in the mornings, but my GP insisted that this is a very good drug with a lot of benefits and advised me to continue with it. I then began to experience some 'stress incontinence'. I put it down to being menopausal. I couldn't confidently cough or sneeze and I gave up playing tennis. Six weeks ago, I decided to speak to my GP again about changing my medication, I was getting more and more 'hung over' in the mornings, but he was on holiday. I decided on radical action, bought a BP monitor and stopped the doxosin. Almost immediately I felt fine in the mornings. Then I suddenly realised that I could cough without embarassment. My BP was a little higher, but I feel that I can live with it if its under 150/90. I looked up doxazosin and discovered that it is also prescribed to relax the bladder and urethra in men with enlarged prostate. I 'd be interested to know if there are any other women on this medication experiencing possibly unnecessary stress incontinence. I will be seeing my GP to discuss my medication regime very soon!

1 like, 27 replies

27 Replies

Prev
  • Posted

    I have only just seen this post when trawling the net for Doxazocin side effects. I am 70 and have been on Dox for about three months, after a disastrous episode with amlodipine when my legs swelled very badly. I have been on BP lowering drugs for many years, as my systolic pressure is naturally very high, often 180 or more, and I have a family history of stroke. When it became obvious that Losartan, atenolol, and bendrofluazide were no longer controlling it, my GP set about trying different drugs, and at first Dox seemed the best of the bunch as far as side effects were concerned. I was on 2mg with few problems, but she wanted my BP reduced a bit more, so we decided to try 3mg. Since then, I have the 'hung over' feeling every morning, and find it very hard to get going. I get back pain whenever I walk any distance, or stand for very long, my eyesight has deteriorated, as everything now looks fuzzy, I permanently have a very dry mouth with an unpleasant taste, and of course the dreaded stress incontinence! Also, I feel permanently tired, but not in a good way. Everything is an effort. Apart from all this, my BP is fine now, so what do I do? I am tempted to go back to 2mg, but I know the BP will rise again so I guess it's back to my very helpful GP to try something else!
  • Posted

    I have actually found that by taking it afternoon wise - it can reduce the need to go running to the loo and also by not drinking large amounts after 08:00pm

    I actually forgot to take the tabets  due to a tummy bug and was amazed at how much better I felt in the morning.. defo on the terrible feeling groggy in the mornings...   Now not sure what to do, as similar to you guys - GP just dismisses my comments as rubbish and tells me to keep on taking them, so wrongs on so many counts.

  • Posted

    I have been taking the usual thiazide  and Enalapril combination for several years and recently my BP increased. GP prescribed Doxazosin 2mg od. am. This was only yesterday and already I feel tired, mentally slow and my mild stress incontinence increased suddenly this afternoon! No change yet in BP. After reading the posts on this page I don't think I'll last out until my next appointment in 2 week's time.
    • Posted

      Yep I have just gone on this and the 4 night trips to the loo are exasperating. Is there no drug that doesn't have this effect? 

  • Posted

    As I said in an earlier post I started taking 3mg Doxazocin about three weeks ago, and felt really groggy, although my BP took the required nosedive. However, I have noticed over the past three days that I feel a lot better, i.e. not so tired and fewer aches and pains, stress incontinence gone. but unfortunately my BP has gone back to its former levels of 160-175 systolic, which indicates to me that the Doxazocin has stopped working. I already take Atenolol, Losartan and Bendrofluazide, but they don't do a lot on their own. The Doxazocin had been lowering my BP to below 130 systolic, so it is a bit scary that it has suddenly shot up with no good reason, apart from the fact that I am stressed out with house selling/moving, and slow solicitors. Oh well, back to the doctor I suppose and no doubt she will want me to try 4mg Doxazocin, which I'm not keen on, but I'm sure she will be running out of options.
    • Posted

      You said your bp had shot up for no good reason apart from the stress of house selling/moving & slow solicitors. That's all it would take! You'd be suprised at how stress can affect bp. I would think once you settled down, perhaps the bp did as well?
    • Posted

      Hello carolyn. Have you found solution with your GP? My mother has very similar problem due to high allergy to many blood pressure reducing drugs. Doxazocin is almost the only one who could do the job without getting her legs swlelled or red dots aka lupus erythematosus. But there is dizziness and other negative symptomes with it
  • Posted

    it is such a a shame.. cos it did bring my blood pressure down.. lol  I even tried taking half a tablet (2mg) of the 4mg  tablets...  my BP was always up  in 180/90s but with taking it, it actually dropped to 120/65 which I havent had for over 20 years lol ..  I am on so many tablets and they wont drop them...  somethimes you just have to make the changes yourself and fight the doctors....  we know our bodies better than the doctors.. and the way we feel.. not saying to disregard their help but they just dont listen and throw anything thing at us and expect us to take it.
  • Posted

    I have just started taking doxasosin as other drugs ave had some side effects e.g. Ramioril made me cough, candesartan gave me headaches and losartan made me wee more at night and made me depressed. This one, after an hour of dizziness, has been  ok so far except for the 4 trips to the loo in the night. Comforting to know it's not just me but what else can you take that doesn't 't have this effect. I am fed up with all the side effects of these things. Tiredness because of interrupted sleep is exasperating. 

  • Posted

    I was prescribed this medication for night terrors but it has not been listed as one of the things to take for that and I'm very confused

  • Posted

    Am I so glad I came across this post as I thought it was me!

    I was on 10mg of Ramapril only when Atenalol was introduced but due to a reaction to it ie a rash and leg swelling I was instead put on 1mg of Doxazosin

    It was at this time I started to get an increase in needing the loo with stress incontinence. I remember reading that it was also prescribed to men for prostrate problems but never associated the two problems as there was nothing noted in the side effects.

    My BP has recently become higher than usual and so my GP has increased the dose of Doxazisin to 2mg. I started my first higher dose this morning. However after reading everyone's comments I'm dreading the day ahead!

    • Posted

      Atenolol is known for causing swelling..it's a very common side-effect of the drug, but some people don't have a problem with it. Just as the old saying goes..."we're all different". 

      Yes, Doxazosin can be prescribed for men with prostate problems, but it's also prescribed for bp control.

      I have a very close female friend who takes Doxazosin (1mg) for bp control & she doesn't have any problems. 

      Usually, pharmacists recommend to patients that when starting Doxazosin, or if the medication is increased, to take that 1st dose or increase at bedtime to alleviate becoming dizzy during the waking hours. Again, my friend had no problem. She took her first dose at bedtime, then started taking it with her other medications during the morning at breakfast. That way, there's no chance of forgetting a medication, & it's over/done with 'til next day.

Report or request deletion

Thanks for your help!

We want the community to be a useful resource for our users but it is important to remember that the community are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the community is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.