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EBV test results help??

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erika66424
erika66424

I have been sick for a while now with sore throat, low grade fever, body aches, slight cough, swollen tonsils, shortness of breath. I have almost all of the symptoms of mono. i was given a mono blood test (heterophile antibodies) and it was negative. I was also given an EBV antibody panel test and these were my results:

EBV Ab VCA, IgM - negative

EBV Ab VCA, IgG - high 50.1 (the reference range only goes to 21.9 for my lab so 50.1 is high)

EBV Nuclear Antigen AB, IgG - negative

I am very confused on what this means as everywhere i look on Google has different meanings. One site said it can indicate active infection and one said it can't be active if IgM is negative, so i'm getting different responses. Can anyone help??

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1 Reply

  • lisa01328
    lisa01328 erika66424

    Posted

    Hi Erika! I'm no expert but the negative VCA IgM and positive VCA IgG suggests that you had an infection in the past (either long time ago or recently in the past). Usually, EBNA1 IgG are positive if the infection happened longer than several weeks/ couple months ago, but I read that some people (5-10%) never generate EBNA1 IgG. VCA IgM will go down after some time. Your symptoms sound a lot like infectious mononucleosis so you might be in that phase where your IgM have already gone down, but your EBNA1 IgG haven't been generated yet. You should re-do the test after some time and see if EBNA1 IgG are positive by then. Take care and hope you are feeling better soon!

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