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Fluoxetine and Rivaroxaban

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Sweetpea56
Sweetpea56

Hi i am new here. I have Atrial Fibrillation and am on Rivaroxaban for this and I have been prescribed Fluoxetene for depression.  My GP did the consultation over the phone yesterday and sent the prescription to the pharmacy.  I rang the pharmacy today to see if it was ready for collection.  The pharmacist has referred me back to my GP and has told me i should not be taking Fluoxetene with Rivaroxaban as it could cause bleeding. Can someone help me with this please.  Thank you.

0 likes, 2 replies

2 Replies

  • bluenoodles1
    bluenoodles1 Sweetpea56

    Posted

    Hello I dont have any idea myself, but from the NICE web-site it does appear your pharmacist is correct

    NICE Web-Site

    RivaroxabanRivaroxaban is predicted to increase the risk of bleeding events when given with fluoxetine. Manufacturer advises use with caution or avoid.

    Severity of interaction:

    Severe

    Evidence for interaction:

    Theoretical

    To go to webisite put this in yiur browser

    https://bnf.nice.org.uk/interaction/fluoxetine-2.html

  • cardiac_congo
    cardiac_congo Sweetpea56

    Posted

    Hi. If you check the side effects of Fluoxetine, it does warn about possible irregular bleeding, and that could be why your pharmacist has said what they have to you. I used to take Rivaroxaban, and it DOES impact your body for things like bruising and cuts - i was black and blue for the first couple of months, and even tiny cuts took quite some time to stop bleeding. Ive never taken the other, but it would appear your pharmacist doesnt want you to take risks, so follow the advice and re-visit you GP would be my suggestion. You need to be safe on your meds!
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