Fully enclosed cancer

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Diagnosed 8 weeks ago. Gleason 4.3= 7

Recommended as a candidate for NanoKnife therapy.

Supposed total ablation of cancer tissue with little to no side effects

Anybody here able to give more info.

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  • Posted

    Don't just focus on the technique, any technique.

    focus on the depth of experience of he who applies the therapy, be it nano knife or radical surgery or something else.

  • Posted

    Ive posted this before, but you may have missed it- Your cancer specialists are in the best position to answer questions because  each of us has distinctly different conditions- i.e. your age,  country of origin, past history, health, previous health issues, etc. The machine you mention is an external beam radiation device, one of many on the market. Usuallt EBRT is just a part of the overall therapy program. In the US, Harvard Medical and the National Cancer Society have published guidelines and pamphlets available online. The latest research and standards are also published online. Below, Ive extracted a portion of the new guidelines. These are for men in the low to intermediate cancer risk, based on your therapist's interpretation of data.

    Table 2: Boosting the effectiveness of radiation therapy

    A randomized controlled study involving 206 men with early-stage prostate cancer evaluated whether adding six months of hormone therapy to external-beam radiation treatment would boost both overall survival and disease-free survival (meaning that the men did not suffer a relapse). The results are given below. The same research group found, in an earlier study, that the addition of hormone therapy was of most benefit to men who were considered at moderate or high risk, based on their clinical profile.

    Five-year follow-up Radiation treatment alone Radiation treatment and hormone therapy

    Percentage of men who survived 78% 88%

    Percentage of men who avoided relapse 57% 82%

    Source: Journal of the American Medical Association, 2004;292:821–7. PMID: 15315996.

    Combined with radiation therapy. A number of studies have shown that men with early-stage prostate cancer are more likely to be cured when hormone therapy is given in conjunction with radiation therapy (see Table 2 above for the results of one study). Even when the disease is regionally advanced, meaning that it has progressed to tissues immediately surrounding the prostate gland, neoadjuvant hormone therapy reduces risk of progression and relapse (see “Evidence for combining hormone therapy and radiation treatment”).

    See harvardprostateknowledge dot org for the complete discussion by Dr Marc B. Garnick, M.D.,from Harvard Medical.

    Another resource is the American Society of Radiation Oncology. They recently published the results of an enhanced study of patients with low to intermediate prostate cancer. Here is an excerpt:

    Ten-year findings from the trial indicate that for men with early stage prostate cancer, there is no difference in mortality rates following active monitoring, surgery or RT, and moreover, that cancer-specific deaths at ten years following diagnosis averaged only one percent for all men enrolled in the trial.

    Growth of the cancer outside of the prostate did vary between monitoring and treatment groups. Rates of both regional spread and distant metastases were significantly higher for men who were monitored rather than treated for their early stage disease. Progression did not vary, however, between the surgery and RT groups, although patients in the trial reported different side effects with each modality.

    “These findings underscore the essential role of dialogue in treatment selection,” said ASTRO President David C. Beyer, MD, FASTRO. “Men with prostate cancer are all different, and the relative costs and benefits associated with the multiple options to treat it can vary substantially between individuals. The best treatment decisions for prostate cancer, or any cancer, take into consideration the specifics of each individual patient’s disease, expectations and preferences. These options can be confusing, and patients should always make these decisions after consultation with a radiation oncologist and urologist”

    Best of luck in your therapy.

    • Posted

      Thanks for your interest.

      I don't want advice on treatments that harm healthy body parts.

      My only interest is in treatments that deal directly with the cancer and cure it or minimise its impact moving forward.

      This is my 3rd cancer.

      Both previous treatments have impacted my quality of life.

      Though thankfully I am here to write about it.

    • Posted

      While you want a treatment that deals directly with the cancer and doesn't impact on your QoL, don't forget to ask any uriolhgsiy you meet

      What Gleason score and tumor types are most suited to Nanoknife?

      What is the five and ten year survival rate?

      What are the impacts on sexual health and urinary function?

      these can best be answers by an excellent surgeon that ideally knows what treatment to recommend based in your biopsy and medical history.

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