GI problems with medications

Posted , 3 users are following.

I was on methotrexate for RA for about 4 years. I developed severe diarrhea after every weekly dose. My rheumatologist switched to Leflunomine 10mg daily. Same result. I am very discouraged. Anyone have this same reaction to both oral drugs? If so, what was your next step?

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  • Posted

    Have not had additional diarrhea due to Methotrexate.  I did have extreme nausea, but they changed me to injections from the pills and I'm doing fine now.   

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