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I've been treated with a variety of eye drops for high eye pressure and now glaucoma (that showed up about a year ago) for about 10 years. I started out with an opthalmologist who was not a glaucoma specialist and was given a variety of medicated eye drops in an attempt to lower IOP. I have experienced a number of different types of negative reactions (one severe) from various medicated drops. I've had a couple of doctors who (in knee-jerk reaction style), if the medications did not lower the IOP sufficiently, changed medications and also increased the number of times a day the drops should be used (i.e. 1 drop every 24 hours, 1 drop every 12 hours, 1 drop every 8 hours, etc), until it felt like the drops were burning holes in my eyes, i was depressed and sick and quit taking any eye drops at all after receiving an IOP of 38. My doctor at the time referred me to a glaucoma specialist. I had with me a list of medications i had taken, and the reactions i experienced from those medications. I took the list to the specialist on my first visit, i told the specialist i felt that i was being over medicated. He was a doctor who actually listened to his patients and we started on a program with the minimal treatment and gradually added drops that i could tolerate until the IOP dropped to 18. So, after one month, i had an IOP of 18 (down from 38) with 1/3 of the medication i had previously been taking and using only timolol (2 drops/day) and latanoprost (1 drop per day) each eye. I had previously had reactions to the latanoprost (not complaining about my growing eyelashes) and he had prescribed the same drug from a different laboratory that he told me was easier on the eyes. We used this combination successfully for about 3 years.
I am not saying that the same combination of drops will work for you, but i am saying that my story illustrates that being aware of the possibility of over medication is important to discuss with your doctor, that discussing side effects you are experiencing is important to do with your doctor, and finding a doctor that specializes or has significant past experience treating glaucoma can make a big difference.
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