Going from split dose to single
Posted , 13 users are following.
I have split my dose almost from the beginning of the PMR treatment. Because of the unusual daily schedule ( work late into the night) I take pred before going to sleep at about 1AM and also when I get up 8-9 AM). When I was at 5mg last fall I attempted to reduce late night dose and had problems and had to go back to 5mg. I was taking 3mg in the evening and 2mg in the morning.
I stayed there until May, when I tried another reduction. This time I reduced morning dose and I went from 5 to 4.5 and shortly after to 4mg with no problem. So now that I am starting next reduction from 4 to 3.5. I still have not touched evening dose, so my morning dose will be cut from 1mg to 0.5mg. I am thinking that I should just take one cumulative dose of 3.5mg in the evening. I know that this goes against usual recommendation that prednisone should be taken in the morning, but I had much better results with current schedule (late evenings).
What are your thoughts and comments? Has anyone done anything similar?
0 likes, 39 replies
Michdonn nick67069
Posted
Hi nick67069, question are you using DSNS method? I split my dosage also and have been reducing both doses a little. Good luck. 🙂
nick67069 Michdonn
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Michdonn nick67069
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nick67069, I would try to reduce both, try alternating days on the reductions. Till you no longer have anything in the morning. That is what I plan on doing with my evening dose. Good luck, think positive, smiling. 🙂
EileenH Michdonn
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BettyE nick67069
Posted
I did not ever split my dose but was changed from morning to evening because, for some reason, that took care of my super hyperness when I took it in the morning so I don't think that evening dosing is necessarily a no no although it does come as a surprise to some people.
Perhaps with your schedule it might be what will work for you. As your dose is now low I would think it would not have dire consequences if it was all taken at night.
nick67069 BettyE
Posted
Thanks! Glad that I am not alone with evening dose. I see rheumatologists every 3 months to get prescription ( regulation here in Japan that you can't get more then 90 days of supply). He was the one that initially suggested splitting the dose because of my unusual daily schedule. I will see him again at the end of September, but by that time I will probably already know the answer if eliminating the morning dose is a good idea.
BettyE nick67069
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BettyE
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The England cricket team are playing a match that begins at 2.00PM and ends at 6.00PM each day instead of the usual 11.00AM to 6.00PM. That makes no sense.
Correction.... that should have read " and ends at 9.00PM"
EileenH BettyE
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kathy61958 nick67069
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Best of luck to you, Nick. I truly hope your reduction works well. I've never had a split dose. I have trouble sleeping without adding prednisone to the problem. I'm on 30mg right now. 4:00 AM is my time to take it. I'm hoping a very slow reduction will be in my future.??
nick67069 kathy61958
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shelleysinclair kathy61958
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shelleysinclair nick67069
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Doesn't the late dose keep you awake at night?
Michdonn shelleysinclair
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Shelleysinclair, I take most of my Pred at breakfast, but 1/4 at bedtime and have no problem sleeping. I just wondered what I going to do as my dosage get smaller. At 17.5 tapering to 15 mg. Still smiling 🙂
nick67069 shelleysinclair
Posted
shelleysinclair Michdonn
Posted
I like your positive attitude. I woke up this morning thinking I better do more smiling or this is going to get the best of me 😊
Michdonn shelleysinclair
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shelleysinclair, I really do believe that a positive attitude is a great help on this PMR journey we are on. We all learn from each other along the way. I just try to keep smiling. 🙂