Gout and coffee

I'm afraid that I can find very little published about pseudo gout. The only recent paper in Joint Bone Spine, Volume 81, Issue 1, January 2014 by Daoussis et al relates to the application of ACTH for it's treatment in a hospital environment. Their main conclusion is:

Adrenocorticotropic hormone (ACTH) may be an alternative therapeutic option for patients with acute calcium pyrophosphatedihydrate (CPP) crystal arthritis (formerly known as pseudo-gout).It was previously thought that ACTH acts by stimulating the release of endogenous steroids. However, experimental data indi-cate that ACTH is not just a “steroid-releasing” hormone but has an intrinsic anti-inflammatory effect related to its ability to bind and stimulate melanocortin receptors. We have been using ACTH as a first line treatment for gout in hospitalized patients since 1995 and have recently reported that it is highly effective and safe.

Could be worth mentioning to a Doctor who treats you?

Thanks.

I have found an interesting paper confirming the efficacy of Cherry juice - and the recommended dosage:

Journal of Functional Foods Volume 11, November 2014, Pages 82–90. Montmorency tart cherry (Prunus cerasus L.) concentrate lowers uric acid, independent of plasma cyanidin-3-O-glucosiderutinoside. By Bell et al.

Exerpt 1:

Montmorency cherry concentrate reduces uric acid and inflammation.

Changes in uric acid metabolism and inflammation are independent of the dose given.

Exerpt 2:

Reports from clinical populations have indicated a reduced incidence of gout attacks following regular consumption of tart cherry juice concentrate across a 4 month period (Schlesinger et al., 2012) and in epidemiological work, patients' self-reported cherry consumption was associated with a 35% reduction in gout attacks (Zhang et al., 2012)

Exerpt 3:

In conclusion, the data from the current study provide evidence that tart Montmorency cherries reduce levels of hsCRP and serum urate and increase urinary urate excretion. Importantly, a 30 mL dose of Montmorency cherry concentrate confers the same effects as a 60 mL dose; therefore from a practical and economic standpoint, it is not necessary to increase the dose in order to elicit a greater response. Overall, these are the first data to show Montmorency cherry concentrate as an efficacious, adjuvant supplement in managing inflammatory conditions, such as those seen with gout, and these observations are independent of CYA-3-O-GluRut absorption in humans.

I have left out their methodology and statsitical analysis, but is is statistically significant (P < 0.05). It suggests that a 30ml daily dose is fine - but taking more has no effect. The increase in urate excretion is also interesting as it may help people with impaired kidney function to lower urate serum levels which is in addition to any dietary change to reduce purine intake. So cherry concentrate can not only be good for prevention - but also reduce the concentration of the uric acid during an attack - aiding the dissolving of crystals already in tissue.

Interesting findings. I'm taking medicine for high blood pressure that has the tendency to raise my potassium levels. I have to watch my potassium intake as potassium overload can have serious consequences, one of which being a heart attack.

Cherries, cherry concentrate, and cherry juice have a lot of potassium and I would need to be careful when implementing this type of treatment. It's an unfortunate reality for me be one I have to deal with, nonetheless.

You find online : The gout Remedy Report,

Download the book and fallow the instructions,

I did myself and it's working,

You have to cut all meats,

I eat only : Tuna, Salmon and sometimes chicken,

Most of vegetables

Hopefully will work for you,

Nico