H pylori, why PPI's?

Posted , 5 users are following.

Hi, can someone give me an answer. I was diagnosed with gastritis due to h pylori infection. I understand the usual treatment consists of two antibiotics and PPI. This last i dont get and i am afraid of PPI's, reading what all bad it might cause.

Is it because this bacteria produce stomach acid travels up so that she can survive in stomach? I have no clue.

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  • Posted

    I dont have any clue why only Ppi for H pylori . I was diagnosed with H pylori two months ago and they put me on 14 days therPy ( two antibiotics and omeprazole ). I did endoscopy and I still have bacteria and now I am on two different antibiotics and proton pump ( p. Bismuth and omeprazole ). The dosage is much stronegr ( 18 pills per day for 10 days /5.000mg strong medication. Didnt have any side effects by using the first therapy. Im on omeprazole now for four months !
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  • Posted

    H-Pylori will be eradicated by antibiotics but to allow your infammation to heal, you need to reduce the acid.

    The scare stories about PPIs are largely unwarrented and any effets that are due to them are only manifest when the drugs are taken inappropriately, at too high a dose and over a long period of time when they may induce hypochlorhydria. (Stories about dementia and chronic kidney disease etc are from studies showing a correlation, not a causation. )

    Visit thw www BarrettsWessex org uk website and find the page on PPI dangers under the Treatments / drugs tab.

    I can also send ypu links (or you can Google) "Assessing the Benefit-to-Risk Ratio of PPIs: Putting The Results From Observational Studies Into Context" research paper released a couple of weeks ago, "Current treatment options for esophageal diseases." research paper released this week or "Acid-suppressive medications and risk of oesophageal adenocarcinoma in patients with Barrett’s oesophagus: a systematic review and meta-analysis" published a few weeks ago that shows PPIs have a chemo-protective effect - so reduce risk of cancer.

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    • Posted

      Thanks for your advices.

      I had endoscopy, they found my esophagus is ok, without scars,damage, but i have inflammed everything in throat area, walls,tonsils, uvula, thats why i first visited ENT specialists, only than it came to my mind it could be gastro/acid/pepsin related.

      I think i have to buy myself a peptest, since i heard silent reflux, (i have no heartburn or pain) is more due to pepsin than stomach acid.

      Inflammation in my throat cause smother like symptoms, i need to yawn a lot and my breathing is not automatised.

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    • Posted

      Buy a peptest by all means but it won't cure your reflux. If it finds pepsin in your saliva, it just confirms you have extra-oesophageal reflux - which you have probably correctly diagnosed yourself with anyway.

      The attached graphic shows the percentage of refluxers who reported various symptoms of reflux.

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    • Posted

      Hi

      I have been diagnosed with reflux, mild to moderate chronic gastritis. I have constant throat clearing. Mucus swallowing. Some post nasal drip. But my most severe symptom is the constant throat clearing. I had h pylori and had it eradicated but I never experienced typical h pylori symptoms. I asked for the test because of the throat and came back positive. My question is will PPI's get rid of my throat clearing. It's been 9 days on 80mg of nexium. Or is it possible I still have h pylori? I had three test saying I was negative but I was on Zantac nothing else. Thanks

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    • Posted

      Hey,

      ?I was diagnosed with H pylori but before the tests came back positive, my doctor gave me PPI (Lanzoprazole) to lower the stomach acid levels in my stomach and stop the reflux (which didn't help me at all, made it worse)

      ?But anyway, I imagine if your throat clearing is due to acid reflux or h pylori, then the PPI should work, as most people have a lot of phlegm as their symptom. Dont be put off by my experience... Im still suffering from acid reflux because I refused to take PPI after day 5, but it's better than the side effects from the drug lol.

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    • Posted

      Me too have a chronic need of throat clearing and yawning to get a satisfying breath, it is very annoying. I think it is more due to pepsin than stomach acid, because i watch out to not lay down couple of hours after a meal. I heard LPR or silent reflux happens more in upward, 'normal' body position, during the day and especially when sitting-there might be a pressure on stomach i guess when sitting. Acidic food triggers pepsin that is present in throat to activate and cause these problems. Correct me if i am wrong.

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    • Posted

      Not yet they want to try this for 30 days but it's been 15 days. My heartburn is gone and the acid in the mouth has all but subsided but the phlegm in my throat is still there after I start to eat and in the morning. I haven't done the manometry test yet nor the24 hour probe test. I think it has to do with my insurance since I have state funded insurance right now.

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    • Posted

      The fact your heartburn has gone shows the PPIs are being effective at their job. You won't need the 24hr pH manometry to prove there was acid unless you are to have surgical treatment (or just want to prove it to yourself) .

      However, although they're good at suppressing acid, they are not so good at the mechanical process of reflux which is the cause of the phlegm in your throat.

      Your reflux needs to be managed by lifestyle modifcation or surgery.

      See the chapters in the reflux section of the free book / website www DownWithAcid org uk

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    • Posted

      Hi Barrets,

      I've changed the way I eat and I don't eat before bed. I still have the same issues. The Gastro Drs put me on 80mg of a PPI because when I told them that when I was on 80mg of a PPI during the antbiotic treatment my throat clearing comepletely stopped. So they figured it would work again. Taking PPI's for any amount of time will not stop the throat phlegm? This is not related to high acid? In other words if I restore acid levels wouldn't that stop the throat clearing? Thanks

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    • Posted

      No.  Anything, acidic or not, aspirating in the throat will produce phlegm.

      You need the PPIs to ensure it's not so dangerous but it's the reflux not the acid that is causing the production of phlegm.

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    • Posted

      I had these symptoms of reflux and many more all my life. I was taken to the doctors when I was 3 or 4 for being a "mouth breather" but it wasn't until I was in my 50's the real reasons for my symptoms were discovered.

      In that time I had numerous tests and they tried many different drugs to reduce nasal congestion. I had asthma inhalers. I had my sinuses flushed. I've been tested (negatively) for all known allergens. etc.

      For me nothing worked until I had the reflux reduction (fundoplication) surgery - which also cured other symptoms I hadn't thought of as being related. (See the Down With ACid book.)

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