Has anyone any experience of using Pizotifen in children?

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My daughter age 11 suffers with migraines and has done for some years now. Recently (in the last 6 months) her headaches have become more frequent. It has been suggested by a Paediatrician that we try Pizotifen but the side effects are quite frightening for a child. Our GP is reluctant to prescribe it and I just wondered if anyone else out there had used the drug on a child.

Any comments anyone has on the use of this drug would be welcome.


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  • Posted

    Hi did you try the medication on your daughter? My daughter aged 8 has just started taking it 2 nights now she has to take the Liquid form as is on non dairy diet due to allergies. She hasn't yet shown any sign of improving and as she has also been diagnosed with acid reflux it seems to be upsetting her tummy as well. I was just wondering if your child has reacted in any way?
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    Great to hear from someone else who has a daughter who suffers too. My daughter has not tried Pitzotifen yet. We are trying all other avenues first. I was interested to read that she is on a liquid form as she as dairy allergies. We have been to see a nutritional expert today who has said that food allergies could be the route of the problem with our daughter's migraines.

    I would be really interested if you could let me know how your daughter gets on with the preventative medicine. I hope that she responds well and that her migraines are controlled. It really is dreadful not only for the children but also as a parent to see your child suffering.

    All the best.

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    My son is 10 (nearly 11) years old and also suffers with migraines/abdominal migraines. He has suffered on and off for about the last 2-3 years. We have put it down to various different things: anxiety, food, getting too hungry, being tired or over excited etc. However, having tried hypnotherapy CDs and trying not to give him foods that contain high levels of histamine, we aren't seeing any improvement. If anything, the headaches are getting worse.

    We went back to the doctors today for the 3rd time in 3 weeks, very unlike us as my son has never even had antibiotics or penicillin before. She has referred us to a Pediatrician and prescribed Pizotifen. I asked the doctor if this was a type of antihistamine and she said no. However, having done a bit of research, it would seem that it is.

    As with all of you above, I am very nervous about giving my son regular medication, especially if there is a possibility of side effects. We are going to make an appointment to see an osteopath who specialises in children and see where that takes us.

    I really don't know what else to do. My son is missing an awful lot of school and also missing out on fun activities that he would normally do. He usually has endless amounts of energy but at the moment he is pale and lethargic with not much interest in anything. Do the benefits of taking the drug outweigh the cons? I don't know!

    As LouiseY1969 above said, it is not only distressing for my son but also has a major impact on the rest of the family. If anyone does have any advice on this drug or anything else then I would be very grateful.

    Many thanks.

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  • Posted


    I have now taken my daughter off this medication after her being it on it for several weeks although it has made an improvement to the migraine this has affected her behaviour causing massive mood swings from very hyper with bags of energy to the complete opposite of being grumpy and tantruming like a toddler the next minute! Although her doctor at the hospital has said that this is a very unusual side affect that he has not experienced before we have opted to remove the medication and possible try something else. I hope that things go better for you.

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