Has anyone been told to maintain a consistent morning diet?
Posted , 8 users are following.
Since an "appreciable" portion of pred is excreted in the urine as well as the bowels, the implication is that PMR-GCA suffers need to maintain a consistent morning diet before they take their pred.
What happens if one morning I have eggs, bacon and a sweet roll and the next morning I just have a cup of coffee and a muffin? I believe that this will affect the amount of pred that was absorbed into the blood or excreted by the bowls. The eggs and etc. would mean that less pred would enter the blood stream. It seems to me that the lower the dose of pred one is on would make maintaining a pre-pred diet even more important!
Prednisone is readily absorbed from the gastrointestinal tract... The preconversion biological half-life of prednisone is about 60 minutes. Prednisolone is excreted in the urine as free and conjugated metabolites together with an appreciable proportion of unchanged prednisolone. Prednisolone has a usual plasma half-life of 2 to 4 hours
0 likes, 15 replies
Lee-Colorado
Posted
old_nanna
Posted
Lee-Colorado
Posted
paula-ann
Posted
EileenH
Posted
There are some medications which MUST be taken on an empty stomach so if you are told to take something without food - DON'T TAKE IT WITH FOOD.
In PMR All your dose of pred should be taken as early in the morning as possible as a single dose. This gives the best results and improves the side effects.
cc - stop obsessing! Relax and take your pills in the morning with any sort of breakfast and then work out how much you can manage to do!
Nefret
Posted
I have only two meds which need to be taken on an empty stomach and I take quite a selection of meds.
When I've compared breakfast food with others there does seem to be a link between us in that the foods of choice mentioned - porridge, muesli, yoghourt, fruit, nuts, honey, go across the board.
Hope this helps.
Light
Posted
I always take my meds after breakfast, which is quite lean, since I'd rather not eat at all in the morning - just a bowl of muesli with walnuts and coconut milk and a fresh fruit salad. I have a coffee an hour or so later.
D_J
Posted
I read all blogs but haven't blogged myself for ages but was interested to know if It really is hampering my recovery from PMR by taking my pred after supper.
I would like to know, although I may have mentioned it in the past, people's opinion on taking in the evening.
If I were to try and change to mornings how would I do it?
I am stuck on 5 mgs having tried unsuccessfully to reduce 4 times over the last 5 months.
Glad to see Eileen H is still around with her ever valuable advice!
DJ
MrsO-UK_Surrey
Posted
It doesn't matter what you eat before taking the Prednisolone (or Prednisone)......just EAT. If you include 'live' yoghurt and Manuka honey, all the better - the 'live' yoghurt will help line/protect the tummy and the Manuka honey can help boost our immune systems and help with esophagus problems etc.
cc23145 - Coffee, like sugar, can stress the adrenal glands, which are already being suppressed by the high dose steroids, so if you can reduce or cut down your intake that may help, especially at the lower doses when those glands will be needing/trying to get up to speed again and produce their pre-steroid supply (cortisol) as the artificial steroid is taken away.
MrsO-UK_Surrey
Posted
MrsO-UK_Surrey
Posted
The 5mg dose can be a sticking point for many people and, if you aren't already doing it, and provided you feel well at 5mg, it can help to remain on that dose for many months (it was 5-6 months for me), and then try reducing in just 0.5mg decrements, tapering on just one day of the first week, two of the second, three of the third etc. It took me about 7 weeks to go from one dose to the next, so a snail's pace, but it eventually got me off Pred. Some people can manage 1mg at a time, but after several years on steroids for both PMR and GCA, and a severe flare at 5mgs, I wasn't taking any chances at 5mg the second time around!
Don't worry about the length of time on 5mgs - there are unlikely to be side effects from this dose.
Light
Posted
I add a pinch (literally) of baking soda to make it more alkaline.
You probably should have added alcohol to that list of sugar and coffee.
DJ, the mornings are largely recommended for your preds as I understand you benefit more in the mornings.
MrsO-UK_Surrey
Posted
[]"You probably should have added alcohol to that list of sugar and coffee."[/B]
What, and make myself even more unpopular with those who are already baulking at the suggestion to cut down on coffee?!!!!!
Lee-Colorado
Posted
Adults: The initial dose is 5mg to 80mg daily depending on the condition being treated, as a single dose after breakfast, as divided doses, or as a double dose on alternate days. The maintenance dose is usually 5mg to 20mg daily. The dose should be individualised according to the severity.
Children: For children up to 18 months of age, dosage has not been established. For children over 18 months, initial dosage is 0.5mg/kg daily, this dosage can be doubled or trebled if necessary, continued until definitive remission occurs. Maintenance dose 0.125 to 0.25mg/kg daily.
A single daily dose is preferable over divided doses, to reduce the likelihood of adrenal suppression. The dose should be taken prior to 9am, to closely mimic the body's own maximum corticosteriod secretion. Giving the dose, usually double pre-determined daily dose, on alternate mornings may also reduce the suppression of the HPA axis. This regimen is not recommended for treatment of haematologic disorders, malignancies, ulcerative colitis, or severe conditions.
Lee-Colorado
Posted