have been diagnosed with PMR after more than a year
Posted , 3 users are following.
Have not started on preds yet as have broken a bone in my foot and have to wait for it to heal. am worried about taking preds and can manage the pain but what I cant cope with is the depression, not wanting to eat , wanting to sleep and not wanting to take part in anything, will preds help with this side of things.
1 like, 9 replies
EileenH vanessa66630
Posted
I can't see why you have to wait for the foot to heal - being on pred at these doses isn't likely to affect the bone healing. I know people who have had hip replacements whilst on 10mg of pred.
mrs_k vanessa66630
Posted
PMR left untreated can lead to complications so the sooner you start the better.
theresarok mrs_k
Posted
EileenH theresarok
Posted
It isn't a case of pred is bad, no pred is better - there is another elephant in the room.
mrs_k theresarok
Posted
EileenH has explained all the others, much better than I can, so please take notice.
EileenH theresarok
Posted
People who have PMR are at risk of developing GCA, which can lead to permanent loss of vision. About 1 in 6 patients who are being treated with pred do go on to develop the symptoms of GCA but usually are less likely to go blind. Patients who have PMR that is not treated with pred are more likely to develop GCA and are also probably less likely to recognise the symptoms: headache, jaw pain when chewing, scalp pain, blurred vision, seeing double, dark patches in the visual field or a feeling there is a curtain in front of the eye. The only safe treatment to avoid going blind is pred - at a much higher dose than for PMR. So not taking pred for PMR may actually result in you needing far more pred in the end.
theresarok vanessa66630
Posted
theresarok vanessa66630
Posted
symptoms seem very similar; what is different between the two?
EileenH theresarok
Posted
The diagnosis of fibromyalgia used to be made on the prescence of a large number of paired tender spots - there are 9 pairs distributed all over the body and pressure on them causes exquisite pain. Whilst this may happen in PMR the points aren't always localised to a particular position. When I was first ill I had several places where I couldn't be touched without pain - some coincided with fibro spots so at first I was a bit confused, it could have been either.
The primary difference though is in the response to prednisolone. PMR symptoms respond to give a 70% improvement with a few days, not pain-free but very noticeably better. Pred has no effect on fibro pain at all. Fibro may respond to amitryptiline - PMR doesn't. This is because the causes of the pain are different. Although it isn't really know what the causes are, in fibro it seems there is something wrong with the nerve connections to and in the brain which cause problems processing pain. In PMR it is almost certainly an underlying autoimmune disorder which is causing vasculitis (inflamed blood vessels) causing swelling so the blood has difficulty getting through to the tissues. The pain is probably due to lack of oxygen supply - at rest it is often OK but on exercise the blood supply doesn't increase. If this happens in the upper body and into the head it can cause GCA, but the name PMR is just a description of the symptoms, they may appear in someone with GCA but in most patients it doesn't get so extreme and a lower dose of pred achieves good management of the symptoms.