HELP anti smooth muscle antibody #positive

Posted , 4 users are following.

Hi,

I have come to know that my antibodies blood test came back and the anti smooth muscle antibody is positive.

I have been reading about it and I am slightly worried.

My gp did a liver function test and ALT was a bit raised up but that could be the gallbladder stones which am getting removed in 2 weeks time.

GP referred me to the liver specialist and not want to further tests.

Anyone ever had the same?

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11 Replies

  • Posted

    Before I gave my gallbladder removed all blood test results higher than normal.

    It's been a few years since I had it removed ,I have mild fatty liver now not sure having gallbladder removed as contributed to this.

    I was advised to Loose weight ,although now 8.11 I was 9.7 and my blood test have all gone back to normal .

    I believe ALT can rise if you have gallstones and they are causing problems so I wouldn't worry ,wait till you see specialist you may be advised to have gallbladder removed.

    The op is usually done by key hole surgery and done in the day ward. Recover about 4 weeks.

    Hope your don't after wait too long for your appointment...holly

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    • Posted

      Thank you holly,

      Lets hope its nothing serious.

      Gallbladder is coming out next Friday and I have been told time and time again that it's a simple day procedure but I am extremely nervous patient.

      For the general aesthetic, was ur significant other allowed to be present?

      I would hate to be alone.

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  • Posted

    It might just be the gallstones, but yes I also have positive anti smooth muscle. For a long time now my ALT has largely increased in a short amount of time, Now I am getting a ALT levels about 500+. I have had dozens of ultrasounds and they suggest fatty liver with mild inflammation, but according to my hepatologist ( liver specialist) a Fibroscan I had at the QE hospital in Birmingham came back with a score of 11.3 which is supposedly early stage cirrhosis. I wish you well and that it isn't anything too serious.
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    • Posted

      In march I had a fibroscan it was 10.1. I was really worried.I was advised to lose weight as I have said earlier.my next fibroscan in may was 7.1. I was told that you can reverse fatty liver and it looks like it is.my next hospital app in in 2 years.I don't drink or smoke.

      My advise to you is stop looking on line it can be really frightening.

      If you drink stop, if you are overweigh try to diet ( not easy ) plenty of exercise.I'm sure you will have been given this advise...holly

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    • Posted

      Hi Chris thank you for replying.

      The gallstones are most likely the reason why my ALT is higher than normal.

      However the anti smooth muscle anti body. Frightens me. Am not a smoker or a drinker. Never drank.

      I had an ultrasound scan and it showed my liver had fat on it.

      My father died of liver cirrhosis, not sure what form or what caused. It.

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    • Posted

      You may have simple fatty liver disease, most cases are mild with little to no symptoms although some cases can progress to Cirrhosis. The liver is a tough organ, even with Cirrhois many can still live a decent life with a good few years - of course this depends on whether the cause can be found. .
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  • Posted

    A positive ASMA suggests an autoimmune condition. If the ALT is also raised it could be autoimmune hepatitis. Was your IgG tested?
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  • Posted

    Hi Moonlightin. I am in a similar situation. Positive ANA's as well as positive (1:80) SMA.... I have had pain under my right ribs for about 8 years now and a bunch of other symptoms. My GP told me the results mean I definitely have an autoimmune disorder he just isn't sure which one but most likely SLE lupus. When I looked up SMA though it came up with type 1 autoimmune hepatitis as the most likely disease. My liver function tests were perfect though... the only other thing that came up was low vit d. Did you end up getting a diagnosis? I hope you are going ok!

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  • Posted

    Hi Moonlightin. I am in a similar situation. Positive ANA's as well as positive (1:80) SMA.... I have had pain under my right ribs for about 8 years now and a bunch of other symptoms. My GP told me the results mean I definitely have an autoimmune disorder he just isn't sure which one but most likely SLE lupus. When I looked up SMA though it came up with type 1 autoimmune hepatitis as the most likely disease. My liver function tests were perfect though... the only other thing that came up was low vit d. Did you end up getting a diagnosis? I hope you are going ok!

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  • Posted

    I had my gallbladder removed after waiting a few too many months - and I may have had an autoimmune reaction. Though y liver biopsy said no evidence of AIH - my primary care and nutritionist think I might be sub-clinical. I am taking good care, eating well, detoxing and my AST and ALT went down below normal. I tested positive for smooth antibody and negative for anti-nuclear. My liver-kidney test less than 1:20. 
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