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I've heard it said by numerous people that they had good outcomes with Prednisone. Someone also mentioned that a good response to Prednisone is a positive indicator of AS. A couple of years ago I had a cervical fusion to try to fix a problem I had at C5-6. After coming out of surgery and for a brief period after thereafter not only did my symptoms from the neck problems subside but my lower back felt better than it has in years. I kidded with the neurosurgeon that he was so good that he fixed two problems at once. But he had no way to explain why my lumbar back felt better. While talking it over with my wife she mentioned that after my surgery the surgeon came out to see her and mentioned that the surgery went well and that they gave me a good dose of Prednisone in surgery to ward off any inflammation from the fusion procedure. He said that this is standard procedure. Sadly and predictably the effect was temporary and soon I was back to my old self.
Since that surgery I have been given oral doses of prednisone on a few occasions for flares of various kinds and NEVER had that kind of dramatic effect. I have been given standard dose packs and even slightly higher oral doses with very little effect on my back.
I really do believe that my lumbar back relief was due to the prednisone given during the surgery. There is nothing else I could attribute it to. I can only guess that the difference is a matter of dosage. Maybe the amount I was given IV during surgery was a more significant dosage than I get in oral applications.
So I was wondering what you have found. To anyone that got relief from prednisone I was wondering what dosage level were you using and how long were you taking it before relief?
This is mainly a question for my curiosity. I have no thought of taking prednisone long term even if I could get an oral dose to work. My wife has had rheumatoid arthritis for many years now. Before getting miraculous results from Remicade they had her on Prednisone. It worked pretty well for her but she ended up needing a shoulder replacement. The surgeon who did the procedure was adamant that Prednisone was the cause of the shoulder problem. He said that it eventually impeded circulation in the shoulder area effectively killing that joint. That was really all the evidence I needed to not take it long term. But again, I am curious about what doses and durations of oral Prednisone was successful against AS.
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