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hello I took mezalazine for 20 years, I was having a lot of flare ups and tests show I have a 12 inch stricture/narrowing I was put on azaphapine but I felt so tired and the soles of my feet felt like I was walking on pins. My specialist changed my tablets to mercaptorurine 2x 50 mg daily originally I was on one tablet and I wasn't too bad since the increase I have the side affects that I had with the azathaprine the tiredness is the main problem I've tried to not let it stop me doing what I want in my leisure time but it's starting to become more difficult as I also gave a full time job to keep down I just want to go to bed as soon as I get in these side effects seem to not be uncommon how do people cope with the side effects ? The only alternative is a operation any advise please ? Jon
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