HHV 6 IgG antibodies high

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I am having trouble understanding my results. My test results were 10.20

Neg  = less than .76

Equivocal = 0.76-0.99

Positive = more than 0.99

I have never seen this type of rating but it is quite high. What I don't understand is that my DR. says that IgG Antibodies just show that you have had an active infection. Of course I have. Everyone has had Roseola!

Also my EBV ab VCA IgG came back high at 221.0 with positive being more than 21.9. But same problem, it only shows that I have had an infection. This time they also tested the IgM and it came back Equivcal, whatever that means. I need to look it up.

My Dr. did diagnois me with chronic fatigue but even she doesn't seem to understand this. Can anyone give me a little help understanding all this. What type of dr. should I see for this issue?

Thank you for any help.

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5 Replies

  • Posted

    The doctor who ordered the tests should be explaining them to you. Otherwise, you might want to see a different doctor. I'd never heard of Roseola before reading your post. I looked it up, and it typically affects children. So I don't know that it would be reflected in your blood tests. I've never had any of my doctors mention Roseola to me.  

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    • Posted

      Hi Jackie, thanks for commenting. Roseola is usually a child illness but as is chicken pox it is a herpes virus. It is labled HHV 6 and can reactive as all the herpes viruses can. I am looking for a doctor that knows more about HHV 6 and EBV.
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  • Posted

    As far as I understand it, IgG and IgM antibodies will rise in order to fight an infection or virus.  If you have had a relevant infection or virus at any time in your life, your IgG antibody will rise to positive and will remain positive.  The IgM antibody, however, will rise at the time of the virus/infection and then fall back to normal afterwards, perhaps after about a year. 

    Equivocal just means indecisive, neither one way or the other, or borderline in this case. 

    It sounds like you have had EBV (or Epstein-Barr virus) at some time in the past, but the IgM is now equivocal, meaning the virus is no longer active. 

    It also sounds like you've had HHV 6 in the past, which I think is fairly common, as you say. 

    The Epstein-Barr virus is the virus that causes mononucleosis, more commonly called glandular fever. So it's probable that you've had glandular fever in the past, probably more than a year ago. This fits with the diagnosis of CFS, as it often starts with a virus such as glandular fever - that's where mine began too. 

    I hope this helps.  I'm no doctor - just a medical typist, so take my words with a pinch of salt! 

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  • Posted

    By the way, if I were you I would try a new doc, just in case. You may have landed with a registrar - not all doctors know their stuff,  but they should be able to decipher lab results. And I'm thinking if she's quick to diagnose CFS then there may be something amiss. Not to say you don't have it - it's a high probability, but with CFS it's often about ruling out everything else you can think of before making the diagnosis, because there are a lot of other issues (minor or not so minor) that can cause severe fatigue and should be ruled out.

    Don't want to sound like a bossy know-it-all, but that's just my thoughts on the matter. :-)

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    • Posted

      Amelia, thank you for your input. I am going to go to my nieces dr as she is being treated for cfs. My IgM antibodies were not tested so I need to go to someone who really knows what all this is about. I was tested for a ton of other things but according to them I am in perfect health! Whatever the problem is, I just want to get it under control.
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