High C reactive protein (over 40)

Posted , 4 users are following.

Hi all,

my Hs-CRP came back high in the mid 40s. I am very concerned if this has to do with CAD or is from some other kind of inflammation. I don't have any infections at this time that I know of.

I have read in one or two places that metabolic and heart related CRP increases tend not to exceed 10 mg. I am hoping mine is from something other than atherosclerosis.

Has anyone here have CRP elevations that turned out to have non cardiac causes?

p.s. I have IST for which I am on Bisoprolol 2.5 mg. Nuclear stress test, multiple echos, ECGs have been normal so far. BP which spiked (diastolic) a month back is now back down to the 70s and mid 80s at most. my last A1C was in the non diabetic range. I was diagnosed with mild sleep apnea. on my cpap, my AHI is down to 4 and below (normal).

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3 Replies

  • Posted

    Hi,

    I had a HsCRP done last August , it was done by mistake, I was supposed to have just

    the regular CRP test, as I have LUPUS and undifferentiated CTD and that test is frequently done to gauge the level of inflammation. I was surprised though when I learned that the HsCRP was way out of range. I don't remember the actual # at this

    time, but I have learned that the common conditions associated with a high HsCRP

    are CAD or a recent infarct. I underwent a thallium/persantine stress test a few months

    ago and it was negative for CAD, however I had what I think was an infarct last June

    during a MVA and was taken to the hospital and had an ECG, subsequently, I was told

    I have a second degree heart block. Never was diagnosed with one before, but my paternal grandmother had an infarct in her sixties and later had to have a pacemaker

    installed. I wish you luck with your followup care.

    • Posted

      Hi thanks for sharing this.

      I have had a normal ECG very recently. I do have an appointment with my cardiologist tomorrow, so I will have a more detailed discussion. I've talked to an NP friend and was informed that commonly, hs CRP (which is basically a more sensitive CRP test) in the 40s isn't from CAD, in which case I'd imagine it'd show up on the nuclear stress test. A CRP between 3 and 10 does increase risk for CAD and often has metabolic causes. Any higher than that and it involves acute inflammation of some sort I am told. If the acute inflammation were heart related like from something like mycocarditis, I'd think it'd show up on the ECG and other tests...but I will really have to discuss this in detail with my doctors.

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