High LDH, Serum value of 277 U/L

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I recently took a full body test and they show a high LDH, Serum of 277. What should I do?

I showed the reports to a physician and he gave me medicine of cholesterol and high BP (the test shows 205 LDL cholesterol). When I came home, I found out that he ignored the high LDH in LFT test.

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9 Replies

  • Posted

    Hi,elevated LDH levels are a nonspecific factor,so i cant really say much without looking at other tests.When you say LDH was tested,do you mean iso-enzymes LDH4 and LDH5,which are found in the liver or LDH in general?What are the levels of AST,ALT,ALP,bilirubin,albumin?

    Also LDH can be elevated due to alcohol usage and thrombocytosis.

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    • Posted

      I've uploaded those values:

      Moderator comment:I have deleted the links to the images as they went to a site unsuitable for inclusion in the forums. Users can upload images directly to this site by using the icon at the top right of reply boxes.

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    • Posted

      Yeah, sure. I've also included the reference intervals.

      Liver Profile- (Liver Function Test)

      Protein Total@

      Serum

      Biuret method

      7.9 g/dL 6.0 - 8.3

      Albumin@

      Serum

      Bromcresol Green

      4.6 g/dL 3.5 - 5.0

      Globulin*

      Serum

      Calculated

      3.3 g/dL 2.3 - 3.5

      A:G (Albumin:Globulin) Ratio*

      Serum

      1.39 1.20 - 2.00

      SGOT/AST (Aspartate Amino-transferase) @

      Serum

      NADH (without Pyridoxal-5’-phosphate)

      18 U/L 5 - 42

      SGPT/ALT (Alanine Amino-transferase) @

      Serum

      NADH (without P-5’-P)

      38 U/L 6 - 55

      GGTP (Gamma Glutamyl-Transferase) @

      Serum

      L-Gamma-glutamyl-3-carboxy-4-nitroanilide Substrat

      32 U/L 12 - 64

      Bilirubin,Total@

      Serum

      Diazonium Salt

      0.78 mg/dL 0.20 - 1.20

      Bilirubin, Direct@

      Serum

      Diazo Reaction

      0.31 mg/dL 0.00 - 0.50

      Bilirubin, Indirect@

      Serum

      Calculated

      0.47 mg/dL 0.10 - 1.00

      LDH, Serum*

      Serum

      IFCC- Lactate to Pyruvate

      277.00 U/L 125.00 - 220.00

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    • Posted

      Since everything in the LFT is normal we can exclude liver disease.As i said LDH is nonspecific factor so it will rise even when there is something minor, like inflamation.Elevated LDH that is up to 5 times over the normal range usually means inflamation,mononucleosis,pancreatitis or parenchymal liver disease(in your case we can exclude this).If the results were like 5 to 10 times higher then the range then it could be something serious.If you have no other symptoms you are just fine.Also do you have CBC and differential done?
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    • Posted

      I had also got my CBC done. It's all normal. Lipid profile as well; only cholesterol is high.

      My doctor said no need to worry about the high LHD, he has given me the medicine.

      But I came home and found he prescribed me for cholesterol and high BP only. Maybe he meant LHD will become normal on its own.

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