High MCV After 6 Yrs Of Treatment?

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Hello, I hope everyone's as well as possible.

I was wondering whether anyone could help with a quick question at all..? I’m 30 and I’ve been treated with B12 injections every 3 months for the past 5-6years for Pernicious Anaemia. My MCV is still high (averaging 105). My doctor and rheumatologist were both clueless as to why it’s still like this on treatment. I was wondering if anyone had any thoughts; how long would these levels ordinarily take to drop back within normal range?

If you’re able to help at all that would be very much appreciated as I’ve nobody else to ask as the specialists don’t seem to know either.

Thank you so much! 😃

Caz

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  • Posted

    Hi Caz,

    My MCV is also consistently at the top end and I've had P.A. for over 46 years

    It is also important that your Folate level is monitored as this is essential to process the B12.

    There is a complex interaction between folic acid, vitamin B12 and iron. A deficiency of one may be "masked" by excess of another so the three must always be in balance.

    Symptoms of a folate deficiency can include:

    *symptoms related to anaemia

    reduced sense of taste

    diarrhoea

    numbness and tingling in the feet and hands

    muscle weakness

    depression

    Folic acid works closely with vitamin B12 in making red blood cells and helps iron function properly in the body.

    I am not medically trained but personally I have taken 1 – Folic Acid 400μg tablet every day for more years than I can remember.

    I wish you well.

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