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High Metamyelocytes and myelocytes

Posted , 7 users are following.

Kassiebeetle
Kassiebeetle

Back on the forum after a long hiatus. Have just had blood tests which showed high Metamyelocytes and myelocytes. Will have repeat tests in 3 weeks time. Is this related to the Pred. Is this a precursor to Leukaemia?

Still fluctuating with Pred can't seem to get past 12 mgms. Look forward to your very valuable input. We are presently having a heat wave in Queensland. My house is 35 degrees inside at night.

0 likes, 12 replies

12 Replies

  • karenjaninaz
    karenjaninaz Kassiebeetle

    Posted

    Kassie,

    I hope you are seeing a rheumatologist not a go and possibly a hematologist. I do not think it's from pred. I had some bizarre proteins in my blood called mgus.,It cleared up with pred.

    • Kassiebeetle
      Kassiebeetle karenjaninaz

      Posted

      Hello Karen. Thank you for your info. At the moment my GP is looking after things but if I have further abnormal results I will request referral to a Haematologist.
  • EileenH
    EileenH Kassiebeetle

    Posted

    Hi - it's ages since you were around isn't it!

    It isn't necessarily a precursor to leukaemia but it does suggest your bone marrow is working hard to produce new cells and they can be raised in response to inflammation. Was your total white cell count normal or was it also raised? 

    There are a whole load of things to take into consideration for the lab and the doctors - even the shape and size of the cells is also significant so until they do all that sort of thing there isn't really a lot of point speculating and worrying. I know - it's easy to say!

    A few more thermal units would be pleasant here - but it is February, just past midwinter so it wouldn't be right! But I'd rather not have 35C overnight thankyou redface

    • Kassiebeetle
      Kassiebeetle EileenH

      Posted

      Hi there.

      I am sure I replied to you this morning???? White cells are normal. Guess Bone Marrow Biopsy would be the next step.

      I hope you are keeping well.

      Neighbours grow veges. They gxve me some parsnips. Yukky!!!!!

    • EileenH
      EileenH Kassiebeetle

      Posted

      I think there are a lot of things they can look at before a BMB!
    • Anhaga
      Anhaga Kassiebeetle

      Posted

      I used to hate parsnips.  But they are delicious either roasted (with olive oil and balsamic vinegar and other veggies), or as part of a very hearty vegetable-bean soup.  We grew them last summer, and my son's arms broke out in a strange rash which at first they thought was shingles (eep) but it turns out his skin is allergic to parsnip leaves!

  • Nefret
    Nefret Kassiebeetle

    Posted

    Take heart, Kassibeetle.  I was sent to Haematolgy twice for the same reason.  Both times by the time I'd got there my levels had returned to normal.  The second time, they did give me another forward appointment just in case, but it was never needed.

    • Kassiebeetle
      Kassiebeetle Nefret

      Posted

      Hi Nefret. Thanks for your encouraging words. Hiopefully all will resolve.
    • catherine34621
      catherine34621 Kassiebeetle

      Posted

      I had a high white blood cell count, I was sent to a Haematologist and it was found to be negative, then my platelet count was high, so I had a bone marrow test and it was all o.k.. I now have low ferratin levels which is related to anaemia, it may not be as bad as it seems.
  • Kassiebeetle
    Kassiebeetle

    Posted

    Hi Everyone. Thought I would let you know that I saw a Haematologist twice. He is happy to just monitor things with regular bloos tests at the moment. He feels that it is the Prednisone that has caused the abnormal blood tests. He wants me to see a Rheumatologist with a view to trying methotrexate. ( I don't think that is going to happen!!!!!) but I am going to go back to the Endocrinologist who diagnosed me with PMR. Just need to get off the Pred. Wouldn't we all like to come off pred. Are there any new drugs on the horizon?.

    • EileenH
      EileenH Kassiebeetle

      Posted

      Tocilizumab/Actemra probably works in PMR to achieve remission, a trial for GCA showed it works pretty well. But someone told me yesterday that in the USA it costs $35,000 per year! She has it covered by insurance by havng it injected at the doctor's office. In the UK the drug itself costs £12,000 per year but isn't available for PMR, just is being used for some GCA  patients and was already available for RA. There are no proper trials showing results in PMR, just anecdotal and prospective evidence. 

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