high pressure and heart beats

Posted , 5 users are following.

only now doctors found the cause of my high blood pressure : elevate level of dopamine and a litle tyrosine. but now i have a problem with a treatment .what is the drugs i need? what is a specialist may help me?

0 likes, 11 replies

Report / Delete

11 Replies

  • Posted

    Usually doctors don't look for a cause for high blood pressure. Just try drugs to treat it. I have used calcium channel blockers. But there are lots of avenues to bring downblood pressure without knowing a cause

    Report / Delete Reply
    • Posted

      Drugs have not helped to bring my labile BP down over the years.

      I have had urine tests to look for a kidney problem, a kidney and head MRI without any cause being found.

      Very seldom do they find a reason for hypertension.

      Report / Delete Reply
  • Posted

    Hi Maxim,

    I'm not sure where you are in the world. Your next step will depend on the country you're living in, as different countries have different medical systems. In some countries you can self-refer to specialists, in others (like the UK) you can't self-refer at all, whereas in yet other countries you can self-refer to some types of specialist but not all of them.

    You say you've seen a doctor already, and the cause has been established. Can you go back to that doctor and ask what the next steps are?

    Report / Delete Reply
  • Posted

    There are a number of different dopamine receptors that play a central role in blood pressure regulation, the amino acid tyrosine is probably a minor player. I suspect this might be the equivalent of your doctor telling you its a virus when you are feeling rough. It sort of means he doesnt know what it is but with a bit of luck it will get better.

    Usually your own Dr will start treatment and the drugs he will recommend will be based on information about you yourself. In most cases they can achieve reasonable control, its only when they can't or if there are certain complications that you would need a specialist. It can take a while to come up with the best drug or drugs to use you might need to try a few, and they will suggest some lifestyle changes.

    Report / Delete Reply
  • Posted

    Lots of drugs lower blood pressure. Some drugs for other ailments have a side effect of raising or lowering blood pressure. No specialist is needed. It seems to be mostly guess work and a doctors experience with what usually works
    Report / Delete Reply
  • Posted

    in own body dopamine is synthesized from tyrosine, so i have high pressure because i have same problem with tyrosine-dopamine pathway . i am organical chemist, and uderstand that : In the drugs market we have 3 types : antogonist of receptors of dopamine, 2nd type is antogonist of synthesis of dopamie ,3rd it is blocks part of receptors to dopamine . i think 2nd type is suitable to the problem but with a big risk because the drugs may cause to increase tyrosine in the body, and it will be more than now. 2 other types dont help to problem with a kidneys because high level of dopamine is still in the blood, and may cause problem with calcium and insuline.
    Report / Delete Reply
    • Posted

      I realise this might be a bit low-tech for a high flyer like you, Maxim, but have you considered lifestyle changes? Salt for a start - cutting back on it makes a massive difference to some people. And how about your weight? Losing just a little weight helped me a lot. Smoking? Exercise? Intake of carbs, especially refined sugars? I suspect that as a scientist you might be a bit sniffy about these factors, but many people on these boards will confirm they work - either alone or in tandem with medication.

      It also depends on how high your blood pressure is, and how old you are. Clearly if you're, say, 25 and consistently have 200/140, then you need to go on medication immediately. If, on the other hand, you're 65 and have 145/80, with an occasional spike above that, you might be able to manage it entirely with lifestyle measures. (As I'm sure you know, we count in mm of Hg in English-speaking countries, vs cm in a lot of the world.)

      Report / Delete Reply
  • Posted

    This is a bit of a puzzler dopamine tends to produce its physiological effects where its produced, free dopamine in the blood stream has a half life of a few minutes. In the kidneys it acts as a vasodilator and increases sodium loss, its usually failure to produce sufficient dopamine that causes hypertension. Kidney damage due to hypertension can also cause problems in dopamine production. Reguardless of all of this while this metabolic pathway might be the cause, you can always consider the end result of the dopamine disruption. If there is increased sodium retention, diuretics might help, if its vasoconstriction then vasodilators. Your doctors will presumably have the full picture and will prescribe accordingly, you will need to go back to them really.
    Report / Delete Reply

Join this discussion or start a new one?

New discussion Reply

Report or request deletion

Thanks for your help!

We want the forums to be a useful resource for our users but it is important to remember that the forums are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the forums is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.

newnav-down newnav-up