Horrendous withdrawal
Posted , 5 users are following.
I've been on Venlafaxine for roughly 4 weeks now, however due to my doctors messing up my prescription, I have not had a dose since Thursday after having ran out. I was on 70mg daily.
Since then, I have felt the worst I have in years. I'm constantly anxious and on the brink of tears, have very poor motor control (I've had to stop driving because I don't trust myself to a) stay awake at the wheel and b) react to my surroundings). Within half an hour of waking up I am phsyically exhausted and don't even have the energy to keep my head up and eyes open. I've been suffering from nausea, stomach upsets and pains, hot and cold flushes (I woke up one night from a horrendous nightmare and my bed and clothes were soaked with sweat, it was very disgusting and disturbing). I honestly feel like I have the flu, plus allergies, plus am going through the middle of a mental break down, it's horrible. I'm scared to go to sleep because of the sweating and vivid dreams, but I can't stay awake because I'm so tired, and because every time I stand up for longer than a few minutes I feel like I'm going to pass out. Not to mention I feel like I'm floating outside of my body and my brain is popping away to itself like there's little bees in there.
Reading around I think this has something to do with not having my meds, which is a bit of a relief (flu before christmas would not be good) but I feel like I'm living in a surreal world at the moment. I was not warned at all that this drug would have any symptoms like this upon withdrawal (I've been on cetalopram, fluoxetine, sertraline all before and occasionally missed doses thanks to doctors not getting my prescriptions right, but it has never had an effect this bad).
I'm just glad I'm not the only one who's been through this. It's very scary being 18 years old and feeling like you're about to drop dead of a stroke or heart attack any minute because you're blacking out and your heart won't stop racing. Just got to try and get through these next 2 days, as that's the earliest emergency appointment I could get after finding out my doc was refusing to dispense. Feel absolutely dreadful and missed so much college and work.
Has anyone found good ways to cope with the symptoms until you can get back on Ven? I rung up my psychiatrist explaining all of this and his answer was "well, that is a shame. I can't see you, though", so...
1 like, 17 replies
Guest scottch
Posted
Other than that I suggest you go to your gp practice and refuse to leave until they sort you out. Anyone prescribing should know how important it is for you not to miss a dose. I'm impressed that you've managed for this long. Venlafaxine has a very short half-life which is why you are suffering so much.
betsy0603 Guest
Posted
The WD from ven is notoriously bad, and just proves how powerful and ultimately dangerous this drug really is. I know - I'd been on it for 12 years and tapering off, having finally put two and two together about mental decline. My hands don't work and I drop things constantly, have fine motor skill deficits, and can't remember things, short term or long.
Moral of the story is please only use this drug to deal with an acute situation, and then taper off slowly when you are feeling good. This drug should NOT be used chronically!
Good luck getting right!
Guest betsy0603
Posted
You and I are not qualified to tell somebody what to take.
betsy0603 Guest
Posted
Guest betsy0603
Posted
scottch Guest
Posted
It's shoddy, and the fact I have to put a second script in practically the moment I get one to ensure they can get it out on time is atrocious, I think. But that's the South West for you.
j17344 Guest
Posted
betsy0603 j17344
Posted
scottch betsy0603
Posted
Thanks for sharing your experiences, I'm hoping I can talk to my psych about this when I see him next and see if there's a less… painful alternative (though the thought of coming of the drug and experiencing THIS again is stomach churning).
j17344 scottch
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Guest j17344
Posted
betsy0603 Guest
Posted
After I had my hellish protraced WD for 10 months, I did reinstate, not having realized what was happening. It was like a light switch had been flipped, my mood lifting within an hour of that first dose. It shouldn't have worked that fast after 12 months if it wasn't withdrawal, as we all know it takes weeks for these drugs to start working.
37.5 mg is the minimum therapeutic dosage. I have tapered down to 29 mg over the past six months, and I feel way better now than I even did when I started it up again. I had been on it for 12 years. The brain is very slow to recover after having it around that long. Slowly titrating the drug down, very slowly, allows the brain to adapt to its absence, since the brain had remodeled to allow for its actions. I am talking 10% reduction of the previous dose per month. Most people don't know about doing it this slowly, especially the doctors, who declare that your original illness has returned if it happens outside of 6 weeks!
I'm not telling you to go off your ven. That is your choice and that is fine. But I do want to leave you with the knowledge about all this. You had a reason for going off ven once before, and you may have a reason again. Hopefully this knowledge will allow you to do so successfully in the future. I will leave you with this following quote from Dr. Peter Breggin's website (he is a psychiatrist) and then I will leave you alone:
Antidepressants: SSRIs such as Prozac, Paxil, Zoloft, Celexa, Lexapro and Viibyrd, as well as Effexor, Pristiq, Wellbutrin, Cymbalta and Vivalan
The SSRIs are probably the most fully studied antidepressants, but the following observations apply to most or all antidepressants. These drugs produce long-term apathy and loss of quality of life. Many studies of SSRIs show severe brain abnormalities, such as shrinkage (atrophy) with brain cell death in humans and the growth of new abnormal brain cells in animal and laboratory studies. They frequently produce an apathy syndrome -- a generalized loss of motivation or interest in many or all aspects of life. The SSRIs frequently cause irreversible dysfunction and loss of interest in sexuality, relationship and love. Withdrawal from all antidepressants can cause a wide variety of distressing and dangerous emotional reactions from depression to mania and from suicide to violence. After withdrawal from antidepressants, individuals often experience persistent and distressing mental and neurological impairments. Some people find antidepressant withdrawal to be so distressing that they cannot fully stop taking the drugs.
Guest betsy0603
Posted
How many times do I have to tell you:
I was ill before I took any medication.
I was ill on many other medications.
Venlafaxine just happens to suit me.
I know I didn't last long enough to fully get over all withdrawal symptoms.
I and my family and my medical team know what the original illness looked like and I recognised it as soon as it came back.
I really really do not suffer from apathy! For evidence look at my responses.
I have not lost quality of life.
I'm not convinced by your evidence for brain abnormalities and brain death, though if this is true I wouldn't care, given the life medication has given me.
Perhaps I should never have been on medication and spent my life unable to move or speak. I spent 3 years of illness in the 1980s and resisted taking any form of medication. I would have died. I actually think you are more dangerous than the many people who think you should just pull yourself together, because you are advising *all* people to come off their medication. Perhaps the majority of people with anxiety and depression don't need anti-depressants and they are certainly over-subsrcibed, but there are a small number that do and I bet my life that I'm one of them.
Guest
Posted
Serum level of venlafaxine is associated with better memory in psychotic disorders.Steen NE1, Aas M2, Simonsen C2, Dieset I2, Tesli M2, Nerhus M2, Gardsjord E2, Mørch R2, Agartz I3, Melle I2, Vaskinn A4, Spigset O5, Andreassen OA2.
Schizophr Res. 2015 Oct 26. pii: S0920-9964(15)30021-9. doi: 10.1016/j.schres.2015.10.021.
".......Venlafaxine seem to be associated with better verbal memory in bipolar disorder and schizophrenia. This suggests a possible beneficial role of certain antidepressants on cognitive dysfunction, which may have clinical implications and provide insight into underlying pathophysiology. However, the current findings should be replicated in independent samples."
RICHARDJ1985 scottch
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scottch RICHARDJ1985
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Great!
betsy0603 scottch
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