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Does anyone know how long it takes this stuff to wear off when it's stopped in elderly dementia sufferers? I see from internet searches that the half-life is only supposed to be about 20 hours, but I'm doubtful about this.
I'm the legal guardian of an 80-year-old friend suffering from multi-infarct dementia, who was given this terrible drug without my knowledge or agreement about three weeks ago, after she became violent with a member of staff at her retirement home. She was put on 2mg twice a day - combined with the Seroxat and Remergon she was already taking - and turned overnight from a strong, vigorous woman capable of pushing a fit young man down the stairs (the reason they prescribed it) to a catatonic husk, unable to talk or move.
After three doses the nursing staff panicked, reducing the dose to 0.5mg once a day, and she immediately went into a terrifying psychotic episode. For 72 hours she ran around the place non-stop screaming with terror, without eating, drinking or sleeping, until the dose was increased to 1mg twice a day. She then returned to a catatonic state, lying in bed completely immobile, and barely able to swallow food or liquids.
In the ten days since then, the dose has been reduced slowly and the drug has now been stopped. My friend, who now has multiple bedsores as a result of the ten days of immobility, is beginning to move a little, but has become extremely restless and deluded - far more so than when the drug started - with the result that she constantly tries to run around and then falls over.
The Parkinson's-type symptoms are slowly improving so I'm hopeful that no permanent damage has been done. I understand that the increase in her psychotic symptoms is due to withdrawal of the drug. My question is: how much of this damage is likely to be permanent?
I'm heartbroken at seeing her in this awful state.
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