How long does Zoloft take to leave you’re system?

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I gave birth 7 weeks ago and my doctor prescribed me 50mg of Zoloft. I took one Monday night (11/27) and another the next night (11/28) I immediately started having really bad side effects which were diarrhea, dry mouth, lost appetite, increased anxiety and just not being able to function. Since I’ve stopped taking it I wake up every morning feeling anxious and unsettled and it will last until the evening. I’m wondering how long it will take before the Zoloft is completely out of my system because I really hate feeling like this and just  want to feel like myself again. Thank you!

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  • Posted

    I am going through the exact same thing thing!! I got prescribed Zoloft just Incase I were to have post partum depression with my daughter, I took ONE 50 mg pill and had an awful reaction, diarrhea, complete loss of appetite, extreme anxiety, a weird fever? And major chills (which isn’t normal for me, i always complained about being too hot before all of this) and for three days after I’d taken it I lost my emotions but they came back. It was completely traumatizing. I am a 21 year old stay at home mom with two beautiful babies and I was so unstable that first week. ): ever since I took that I’ve still had morning anxiety and some depression after having the anxiety. It’s been about 4 weeks since the reaction. I still don’t understand what happened to me. The doctor and hospital put me down as having panic disorder and started trying to diagnose me with a bunch of bull s**t. AND KEPT TRYING TO PRESCRIBE ME MORE ANTI DEPRESSANTS AND BENZOS?!?! I only took the stupid pill because my 10 month old had croup cough and I hadn’t slept but 2 hours the night before and her cough was freaking me out. I was hoping the Zoloft would take the edge off the anxiety because my doctor acted like that’s how it works. No I know that anti depressants are NOT to be handled so lightly and can be extremely dangerous. And should only be prescribed to people who truly do need them. But ever since I took that stupid pill I’ve been an emotional wreck. It’s eased up a lot but this anxiety and depression is so rough 😩 all those times I claimed to struggle with emotional problems as a teenager are a freaking joke lol I had no idea what true anxiety and depression felt like until now. I have dreams every night about being anxious and restless and depressed and then wake up anxious restless and depressed! It’s eases up a lot into the evening and most nights I feel almost 95% better but it starts all over again in the morning. 

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  • Posted

    Oh and to answer our question it really depends on how quickly your body metabolizes Zoloft, it has a half life of 26 hours, so it takes about 5 or 6 days on average. I don’t believe that was the case for me because i metabolize things VERY slowly. And my stupid self took supplements the week after the reaction because I thought that they would help me get better quicker which I think made things much worse a recovery take a lot longer. 
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    • Posted

      Wow this is really scary!! I thought by now I’d be ok but I’m still feeling a little anxious.  Can I ask what you mean when you say you took supplements after your reaction? I can’t imagine myself feeling like this for another month. I hope you start feeling better soon.
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    • Posted

      It’s pretty scary but I think you should be okay as long as you stay away from anything too stimulating like caffeine or too much sugar and definitely other medications. I’m actually on a site called surviving antidepressants where I have learned ALOT about adverse reactions, I just discovered this site the other day so I’ve been researching it a lot which has helped me understand what happened to me. but after I had the reaction me and my mom were trying to figure out something that could help me since the doctors refused to believe that the medicine did that to me, I tried taking St. John’s Wort which is an herb that is supposed to help with depression and anxiety but i didn’t know that it would just exacerbate the symptoms and make recovery from my adverse reaction take longer! And I took it two days in a row. Along with Kava Kava lol but it’s alot better now than it was in the beginning. This morning is actually the first morning I’ve woken up and not had extreme anxiety! So I’m happy about that. 
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