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I am finding I get irritated and short tempered the day after taking Mtx

Posted , 3 users are following.

valarie61454
valarie61454

This mood change has just started about a month ago. At first I didn't realise I was getting this way. But my husband has mentioned it "softly" a couple of times. Started Mtx in Nov 2017. I am a easy going person who does not typically anger easily. Usually seems to last about 36 hours after I take my meds. I also take folic acid. I have RA. Off and on joint pain all over for years. Thought I w a s just "getting older". I am 52. Only minimal damage in my hand so far. DDD in spine, I swear, I think it is in my knees, hips and spine too, as those joints are where I hurt most. Dr doesn't seem to worry about those joints though. anyone one else have these issues? Haven't read as much about the anger or large joints causing more problems.

0 likes, 4 replies

4 Replies

  • Lilly_1952
    Lilly_1952 valarie61454

    Posted

    Hi I have been taking Methotrexate for 7 week now I am not very good at all 😥

    I hurt more than usual I am moody and so so tired 😴

    But it's the hurting I know I did before this med but my god I do hurt

    I take 10 mg weekly and folic acid on other days I am also still taking sulphazine until the Methotrexate gets in my system blood tests every 2 weeks not showing any difference inflammation markers still high also my blood is thick

    Such an effort to get out of a chair

    I hope you find some answers as my doctor is just not listening

    Started off with Polymylagia 8 years ago then my Specialist said it's let me with Osteoarthritis 😢

  • marguerite63709
    marguerite63709 valarie61454

    Posted

    I’m in tears reading this. I am 31, mom of four little boys, have 3 pups, and a wonderful boyfriend. For years I was a single mom and I was a fighter. Happy and loving, patient and calm would have described me. The past 3 years I have gotten sicker and sicker with my RA. I have flare ups all over my body but as of right now, they have only diagnosed me with that one autoimmune disorder. I have problems with my adrenal gland, kidneys and bladder, also heart issues now. I was dealing fine with everything until the pain in my hips was unbearable. My doctor has me on Otrexup once a week. I have become a monster. My anger management and impulse control are through the roof. I’m scared to be left alone with my children. I’ve been on it once before in pill form but could not get it down. I lost 35lbs before they took me off. We waited a few months and two months ago started this. I noticed a little bit of hostility and agitation but the last three shots have scared us all. Yesterday was my last shot but I am so shaken by the events of the last two days. Why hadn’t a doctor warned me of this? I feel a little better knowing I’m not alone because I felt like maybe it was something wrong within me.  Valeria I hope you get better! I’m finally done with three months trial they put me on. I’m not sure that’s ok for anyone to go through. Oh! And I am not currently on any steroid. 
    • valarie61454
      valarie61454 marguerite63709

      Posted

      So sorry to hear the pain you have been through, emotionally and physically. What a crazy disease. They upped my Mtx, so I am back to some symptoms. Can't afford the injectible. $400 a month. I have some issues with my bladder, need to bring that up next visit. Scared of the other issues popping up.

    • Lilly_1952
      Lilly_1952 valarie61454

      Posted

      So sorry to hear Valarie so expensive for you 😖

      I live in the UK and of course being 66 years old do not have to pay for my medication so very lucky

      I developed sepsis 6 weeks ago so off Methotrexate for a while until things settle down

      Just been for MRI on my left hip and knee see the specialist again on 31St August looks like replacements

      I have had my right side done x

      I do hope things settle for you

      And you can get out of pain it's not easy

      Take care xxx

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