I had been prescribed Azathioprine (150mg/day) in conjun...
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I had been prescribed Azathioprine (150mg/day) in conjunction with prednisolone (20mg/day) as a means of transition off of the steroid treatment.
Shortly after a week of taking Azathioprine I became unwell; completely lost my appetite (due to sometime feeling full or even sick); developed a high temperature; had some dizzy spells; experienced severe aching in joints and muscles from head to foot; developed a severe outbreak of spots all over head and neck as well as on chest back and limbs to a lesser extent.
Unfortunately I had thought that the initial effects that I was seeing (temperature, aching) were associated with lowered resistance to a cold to which I had been exposed, rather than an actual reaction to the drug.
Fortunately I had been in close touch with my GP that week and his support was excellent. Once off of the drug the reversal of symptons was very quick, most within a day, and now only a couple of days later I feel much better again, and only a very small proportion of the spots remain.
In hindsight I can see how ill I became, but at the time I think that mentally I also couldn't function efficiently (conversation and concentration were extremely difficult) making it hard to see how its effect had been gradually worsening as I continued to take the drug. I think this shows that it's important to remember how side effects can build up gradually and not always appear instantly one or two days after you start a course of treatment.:ill::ill:
[i:b921c9e26b]This message was automatically imported from the original Patient Experience[/i:b921c9e26b]
1 like, 4 replies
Guest
Posted
adelelisa1981 Guest
Posted
My crohns is in my terminal illeum and is active following a sample result showing inflammation levels of 448 (normal is 1-60) so im guessing mine is pretty high.
I feel 100% fine in myself which is why im so scared to take something when i feel 'normal'
Jokuar Guest
Posted
Then started Azathioprine 9 days ago. Fine until yesterday day 8 when instantly feltĀ flu symptoms fever/high temp and sickness and some diahorrea. Felt unspeakably bad and listless.
Decided against taking Aza today and have slowly felt better.
IBD nurse said 8 days is unusually quick to have a reaction to Aza as it's usually 2-4 weeks if at all and maybe I had just caught a bug. Hmm.
have been advised to leave off Aza for 3 days then reintroduce Aza from Sunday but to split the doseage between early and later in the day.
Any experience or comments would be appreciated as I am convinced this was a reaction to Aza.
Jokuar Guest
Posted
I started on Aza again on the Sunday evening after dinner and within 2 hours I developed the same symptoms as before. High temperature, sickness and diahorrea general feeling of lethargy and being unwell.
I advised nurse and have not taken it since. As before symptoms cleared within 24 hours when I stopped taking the tablets