Idiosyncratic reaction to antihistamines

The last antihistamine I took on purpose was in 1995. The doctor told me this was a 3rd generation antihistamine and I should not have a problem. I took a 60 mg tablet, cut it in half and then cut the half in half and took about 1/4th of the dose. Then I started my stopwatch and sat down with a notebook and the stopwatch. In 7 minutes I started a headache, within an hour I was dizzy, my balance was affected and I tended to drift to the right when I walked. It was about 46 hours before I felt almost human.

The body produces its own antihistamine and when I hit some level, I would tip into a two week dizzy spell. I had a migraine, dizziness, balance problems and for the first 3 days I had loose bowel movements. I had gotten tired of telling the doctor that I felt like crap so I started a log. Between the 1st of January until the end of September in 1993, I had 5 dizzy spells. I was sent to an ENT group and one of the doctor's wanted me to try something, but didn't want to tell me. He finally said it was a Histamine injection. I said ok and we started the injections. We discovered that 0.30 ml was the correct dose.

We discovered that I could miss 2 injections and if I had the 3rd shot on time I didn't tip into the dizzy spell. If I missed 3 shots, I would start a dizzy spell, but I could shorten the dizzy spell by having an injection of histamine. We don't know why the Histamine shots keep me from my dizzy spells, but it works. The injection doesn't stop a dizzy spell from an Antihistamine so I am very careful to not take an Antihistamine.

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