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Igg tests

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sehla40389
sehla40389

Im very confused abt hsv tests i have done. The first test i did was a combined one showing igg 28.8 positive. Then went for a type specific test which only showed positive igg of 1.9 for hsv1..can somebody help me interpret

0 likes, 22 replies

22 Replies

  • FelizCastus
    FelizCastus sehla40389

    Posted

    Saw this just now! What was your HSV2 IgG score? Were the two test kits (combined and type-specific) the same brand?
    • sehla40389
      sehla40389 FelizCastus

      Posted

      Hsv2 igg score was 0.10 igg and 0.32 igm where positive is greater than 1.1. I dont think the two test were same brand the combined one was chemilusence (clia) ..the type specific test was sent to be done abroad as ot is not done in my country and in the report it did not specify which test
    • FelizCastus
      FelizCastus sehla40389

      Posted

      Seems you may have HSV1 (low positive), which is very common orally and without symptoms, so possibly what you have. You do not have HSV2.
    • sehla40389
      sehla40389 FelizCastus

      Posted

      This is what drs have been saying..but what abt the high positive in the first test..i went to get tested because i was having vaginal itching which wasnt getting better..and felt some pimples..unfortunately did not get them swabed bcs didnt knw wat was having..and drs didnt see them as hsv lesions..

      I tested after 23 days of believed exposure and got the 28.8 in first test..and retested after around 9 days for type specific and got the other result..in those 9 days the dr put me on 200 mg acyclovir daily..

    • FelizCastus
      FelizCastus sehla40389

      Posted

      The combined test is probably using a different reference range/scale. Not all herpes IgG tests use the same scale, so you can't compare numbers across kits. Apples and oranges. 3-4 weeks after possible exposure is too soon to be conclusive. Try retesting in 3 months if you're still concerned.

    • sehla40389
      sehla40389 FelizCastus

      Posted

      Can i take it to be an oral infection then..view that i have no genital lesions and the itching got better with anti allergy meds and have no other symptoms apart from vaginal dryness which is causing burning..

      If i retest in 3 months i redo the type specific one?

    • sehla40389
      sehla40389

      Posted

      And what does a low positive mean for hsv1? I read that it only applies to hsv2
    • FelizCastus
      FelizCastus sehla40389

      Posted

      Probably oral, and always do the type-specific tests. The combined test isn't helpful when positive. Positive for what? Could be either HSV type, so you end up needing to type it. May as well test by type to begin with.

    • FelizCastus
      FelizCastus sehla40389

      Posted

      Possibly nothing. But it is on the low side, so I was just making an observation. Yes, usually a low HSV2 IgG value is consisted suspect, especially in the absence of symptoms but presence of pre-existing HSV1. No such known issue with HSV1, though.
    • sehla40389
      sehla40389 FelizCastus

      Posted

      Do you know if antibodies can go down?..and also do you how to get a confirmation of ghsv1 if there is no active lesions in genital area?
    • FelizCastus
      FelizCastus sehla40389

      Posted

      As answered in your other more recent post, yes, antibody levels can come down. The only way to confirm herpes in the absence of lesions, regardless of type, is by IgG or western blot, but neither can tell you where the infection is located, only that you have it somewhere. Swab tests are thus the most useful and direct test method, but require something to swab, obviously!
    • sehla40389
      sehla40389 FelizCastus

      Posted

      If someone doesnt have lesions in genital area but having tingling can it be assumed it is not ghsv1? Is it safe to do so?
    • FelizCastus
      FelizCastus sehla40389

      Posted

      If you are IgG negative for HSV1 and never had lesions, then yes, you can assume that, as what else can you do? If you are HSV1 positive and never had lesions, then that's harder to say, but chances are you carry it orally. Genital HSV1 is less infectious, so you needn't worry quite so much about it.

    • sehla40389
      sehla40389 FelizCastus

      Posted

      Feliz i just learned my type specific test was elisa and the combined chemilunescence immunoassay..which i should trust
    • FelizCastus
      FelizCastus sehla40389

      Posted

      You can, or you can try a different type-specific IgG test kit first.
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