Increased dose to 300mgs

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Hi,

I started venlafaxine 3 months ago and had been on 225mgs for 10 weeks. I noticed slight improvement but not enough to function normally. I lacked energy and motivation and still felt low. So pysch increased me to 300mgs a week ago. Since then I am totally exhausted, spaced out and really tensed. I feel like I’m really stressed physically like tense muscles in my neck/shoulders and feel irritable. Has anyone else felt worse on increasing or had any of these side effects? I’m worrying a lot. Thankyou 

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  • Posted

    hello, i recently saw a pysc, and had my dose increased from 225mg to 300mg just over a week ago, after being on ven for almost 5 months. took higher dose for a couple of days, didnt like spaced out feeling, dropped to 262.5 mg. have felt better since. if i need to, i can go up to 300mg at a later date. with you being om ven for only 10 weeks, its not surprising you are more anxious. most people get more amxious for a few weeks after a dose increase. id always increased ven doses by 37.5mg since being on 150mg, and havent felt an increase in anxiety. if its unbearable, you could ask your pysc for a low level benzo to help, until the higher dose is working.
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  • Posted

    just to add, improvememts on ven didnt start for me until id been on it for approx 10 weeks, when id just increased to 225mg, so it took a long time to get going.
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  • Posted

    just to add. increases in ven of 75mg are a bit larger than going up a dose with other anti depressants. i think the spaced out feeling is the higher ben dose starting to work, in that it initially knumbs you. when it happens with me, usually leads to a positive result after a couple of weeks. a few weeks after going up to 225mg, for a whole week i felt rigid with tension, and thought id gone to high. lois on here said dont drop, as i was going to. i didnt, and after a week it passed and hasnt returned. both of your symptoms suggest the higher dose is starting to work, and shouldnt last more than a couple of weeks. if you are coming out of a deep depression, to come out of it fully, i think its inevitable that you have to go through these initial side effects.
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