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inflammation in Joints getting worse

Posted , 4 users are following.

robert271163
robert271163

I have had the results of my first blood test back since starting Methotrexate although there are no signs of damage to any organs my Inflammation markers have gone through the roof. 

When i was first diagnosed with PA and i was started on Sulfasalazine my markers were at about 27 then then steadily went down to 7 which was great and i was getting a lot less pain in the joints, But then as my body got used to that med and the pain increased i was put on Methotrexate after getting my results back from my Bloods yesterday my markers have gone up to 30 which is higher than i have ever had them and will explain why i am in so much pain i know it takes time for the meds to kick in and start working but as i am still taking Sulfasalazine as well as the Methotrexate i didnt think the inflammation would be as bad as it is.  Yes i have good days i recently had two good days with little or no pain in my hands but then when the pain comes back it is really bad i often get bolts of pain like some one has pushed a steel rod into my hands / fingers and toes the pain is getting worse at the moment i have lost grip and strenght in my hands i feel so weak at times.  

1 like, 5 replies

5 Replies

  • cat_lady_66
    cat_lady_66 robert271163

    Posted

    Unfortunately I don't think we , who have PA will every be "free " of some sort of pain and weakness in our joints.........I have had PA for 20 + years and I am just getting over the worst flair up ever.........this has taken 4 months to get some sort of relief ..............I take Methertrexate for 18 years 25mgs per week and still have very bad times.........my markers have been around 40 for years now - did get to 100 at one point.........sadly it is something we have to live with..........I'm not very good at "resting on my bad  days" and as I live alone who else will do the daily jobs.........they now want to start me on Humeria as well as methotrexate - hell I'm not sure about that - too much to cope with......... I think you will have to speak to your consultant and tell the. What is happening to you and see what they come up with..........I have taken prednisalone for the past 2 year and finally stopped last month - but they really helped - take care and let me know how you get on...
    • robert271163
      robert271163 cat_lady_66

      Posted

      Hi Cat Lady 

      and theres me thinking i was in pain omg my markers are no where near yours so i can only imagine the pain your in i know there is always some worse than me but have no concept of what pain they are in. I intend speaking to my consultant at our next meeting at the end of this month, The Aim was to get me back to as near as normal as i was before this Thats what i was told however i have got worse than when i first saw him. I have changed my Diet i no longer work due to losing my job due to my condition and yet i am no closer to being any better. I am Lucky that i have a very good wife that looks after me 

      and without her i dont know how i would go on.

  • grimesjeanine
    grimesjeanine robert271163

    Posted

    I iwas on Arava with a good result for a while then I was suddenly in severe pain.  I also developed an infection that I could not get rid of.  I got off the Arava and the infection went away and my pain resolved almost completely.  Try getting off the methotrexate and see if the pain gets better.  Talk to your doctor also and find another medication that may work.  
    • robert271163
      robert271163 grimesjeanine

      Posted

      Hi Grimesjeanine 

      I was getting worse when i was just on Sulfasalazine thats why i have been put on Methotrexate alothough my condition has not improved it has got worse but is that becuase the Methotrexate has not started working yet or is it making me worse im not sure they say it can ake upto 3 months to work i have only been on it for a month, I am hoping that it does start working but until I have given it a chance to start working if it dont then its back to the drawing board and trying a new drug. 

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