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Interesting read on leukocytoclastic vasculitis (LV), tests and treatments

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alex342017
alex342017

hello everyone, I want to share a recent article I found interesting and quite understandable: http://www.mdedge.com/ccjm/dsm/11711/rheumatology/leukocytoclastic-vasculitis

It helped me clartify that I had done all the tests required and that the diagnosis was correct. It also helped me understand available longterm treatments. And in which category of treatment I currently am (depending on the severeness of the vasculitis and the resistence to treatments.)

Cat. 1: colchicine, dapsone, hydroxychloroquine, pentoxifylline.

Cat. 2: immunosuppressive like azathioprine, methotrexate, mycophenolate mofetil (I recall my rheumatologist said the latter is not compatible with pregnancy), leflunomide

Cat. 3 (not compatible with pregnancy): cyclophosphamide, rituximab.

In germany where I live we also get ciclosporin in the Cat. 2. It is however not listed in the article. As for the rituximab (biologic agent) it has only been allowed to treat LV this year in Europe. We do not have much experience and feedback in that field. 

0 likes, 3 replies

3 Replies

  • rocky31676
    rocky31676 alex342017

    Posted

    Diagnosis is only by Biopsy, and should be done withing 48 hours of the new lesion
    • alex342017
      alex342017 rocky31676

      Posted

      That is correct. The hospital carried out a skin biopsy on two of fresh lesions. This is how I was diagnosed too.
  • paul38503
    paul38503 alex342017

    Posted

    Thank you Alex for this list etc.

    Outlining the catagories is very helpful.

    Cheers,

    Paul

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