Is it safe to go from 15 mg of Mirzatapine to 30 mg.

Posted , 4 users are following.

I was on Venlafaxine for 10 years but they suddenly stopped working. My GP prescribed various drugs, mostly SSR!s but they didn't work at all. I went back on Venlafaxine and they worked for 5 months then stopped working again. My GP then prescribed 15 mg Metazapine and I couldn't

believe it when they worked straight away. I was really happy for 3 months but I am back to normalnow. My doctor was going to put me on 30 mg in the beginning but when she saw how good I was on 15 she left it that. I know if I go back to see her she will just put me on the 30 so I would like to know if there is anyone there who is on 30 and how they feel.

0 likes, 4 replies

Report / Delete

4 Replies

  • Posted

    Hi Patricia, I was on Amitriptyline 20mg for short while but couldn't get on with them and still felt low. My Dr decided to try me on Mirzatapine 15mg for a week then up to 30mg. I haven't been on them long just the 2 weeks so far, 15mg seemed to give me a lift in feeling but not sure as I wasn't on that dose for long.

    30mg has made me quite sleepy and lethargic. When I take them at night, I don't fall asleep straight away but then fall into a deeper dreamy sleep which I find hard to come out of. In the morning I feel very tired with a dry mouth and have a job getting out of bed, which put down mainly to my depression. I have experienced bloating and increased appetite and a desire to eat lots of chocolate and have put on a little weight. I can't honestly say that I'm feeling much happier but hope that as I get used to them that they will lift my spirits.

    Report / Delete Reply
  • Posted

    Thanks for your comments Stephen. The 15 mg were great for 3 months but I did feel hungry all the time

    and craved sweet things. It really is a problem knowing what to do for the best.

    Report / Delete Reply
  • Posted

    Patricia, I am curious to learn how and why you say 'they suddenly stopped working'. To be on venlafaxine for 10 years seems excessive and I wonder if your GP monitored you and how you felt during that time. Patients on any medicine need some monitoring and most GPs tell us to come back in xxx weeks time.

    This site has a very specific guide sheet on Mirtazapine for depression and I think you should read it before anything else. You will find it under the medicines tab at the top of this page. It seems to be a well used article because it is high up on a Google search. There is also another forum thread specifically on Mirtazapine.

    Report / Delete Reply
  • Posted

    Hi Patricia, I have been taking 30mg mirtazapine for almost 8 weeks now. 30mg is the dose I was started on. In November I was prescribed 20mg citalopram but after trying that for 8 weeks and having no improvement my doctor decided to change me to mirtazapine with the hope that it would work better for my insomnia, and it certainly did. As I understand there can be some issues with increased anxiety and other side-effects with a dose increase but I can't give you any experience of this because I have been on 30mg from the beginning. Why do you think your doctor will increase your dose? If you are doing well on 15mg then there should be no need for your doctor to increase your dose. Make sure that you tell them how you feel, you are entitled to make a preference in your treatment.

    Best wishes.

    Report / Delete Reply

Join this discussion or start a new one?

New discussion Reply

Report or request deletion

Thanks for your help!

We want the forums to be a useful resource for our users but it is important to remember that the forums are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the forums is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.

newnav-down newnav-up