is it usual to have increased aniexty n headaches two weeks into taking setraline?

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I have been on 50mg setraline for two weeks for aniexty at first I had bad headaches and nausea these seemed to pass after a few days and felt great. The past few days I feel like I have gone backwards the headaches and increased aniexty, feeling nausea n not sleeping well is this common after two weeks? When are the side effects likely to stop? As I'm finding it difficult to do anything and worried that I won't be able to return to work in two weeks time if I'm no better. Also when is the best time to take the tablet? Any help and advice would be great.

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6 Replies

  • Posted

    My doctor started me on 25mg for one week and then increased it to 50mg 4 days ago for my anxiety, I am still feeling anxious and suffering from a lack of interest in nearly everything. I am also taking Mirtazapine for depression. I am just being impatient as I just want to feel better now. I guess I just have to persevere but it is so hard. My doc says to take the tablet in the morning. Xx

  • Posted

    Hi Claire,

    I have been on this med for a few years, with only one break I manufactured myself simply because of the tiredness that it, and at least three other meds I take, were causing. With a demanding job at age 63, it is a battle to work on such medication. But the triedness is one side effect I have never been able to find an answer for, although I space the meds out in a more disciplined way now and lately have been taking the sertraline late at night. That seems to help. The other side effect was easily taken care of: nausea. That only is a problem for me if I take the med without food in the morning, which is not recommended anyway I would think because you need to take medicine with food most of the time. Not sure if it causes headaches. I don't recall thinking it did, but I do have headaches sometimes anyway, with or without under a lot of stress at times and tend to worry about things my friends tell me are no big deals, or things i cannot change. I just look at our insane politicians in the U.S. and the many dumbed-down voters who enable such idiots and am glad I haven't lived there for 30 years sometimes.


  • Posted

    Thanks for advice. Hopefully in a few days I will be alot better as cannot cope for much longer with these side affects. X
  • Posted


    Believe me ,every time I get put back on sertraline it will take a minimum of 5 weeks for me to feel any benefit,the side effects for me are horrendous but when it kicks in it makes a big difference to my every day life.

    I would advise you to have at least 10 CBT sessions,it's not everyone's cup of tea but once you are into it you will learn a lot about yourself.

    Stick with it and hopefully you too will feel much better.

    Good luck,

    Andy M

  • Posted

    Thanks really don't want to take today's one as been bad with headaches all day and don't want to feel

    worse. Does anyone know if a different manufacturer makes a difference? As I wuz first on lustral setraline

    now I've been given a different sertraline but they don't say lustral on them and by a different manufacturer?

  • Posted

    Hi Claire . Yes I had increased headaches and anxiety in the first four weeks .it was awful like you say. I lost my appetite too. I am now on week 8 and just starting to feel less anxious and my appetite has returned . I still have a racing heart at times. I went back to my doctors on Friday and he said continue at 50 mg atm and he gave me propanorol to tAke when have a racing heart as will treat the physical symptoms whereas sertraline will treat the anxiety . He said it can take a good couple of months to start working.

    I became anxious after suffering from labyrinthitis for two years which causes dizzyness etc

    Do continue you will see an improvement even though at the moment days seem so long etc

    I have another brand now but my doctor says there is no difference.

    Good luck Claire keep us posted xx

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