Is liver damage linked to my failed ceramic hip?

Posted , 9 users are following.

This is a bit of a deep subject for the THR forum - but here goes.

After reading another post, I am wondering if my low Factor 7 (blood clotting) which was found at the revision of my hip replacement following catastrophic failure of the ceramic liner and debris from the failure is linked at all.

I know that Metallosis can affect the liver function, could I have suffered some metallosis, or could the ceramic debris be to blame for the apparent liver cirrhosis which has caused it to not produce normal levels of Factor 7 for blood clotting even with high doses of Vitamin K.

I guess it's going to be something else to ask the blood specialists at the haematology clinic and my surgeon.

By the way this is EXTREMELY rare, I am one of about 65 people in the UK with it, and unlike me most of them were born with the problem.

Graham

0 likes, 7 replies

7 Replies

  • Posted

    Hi Rocketman

    My haematology was a long time ago, but I seem to remember that factor 7 deficiency is usually a recessive inherited condition of varying severity, also known as Alexanders disease.

    The possibility must surely be there that it could have been precipitated by your previous experiences when your replacement shattered.

    one to ask the haematologists. For your own research the haemophilia website also gives details of the many other clotting disorders

    Be interesting to know

    • Posted

      Thanks Maggie,

      You are right, it is usually a recessive inherited condition, but I apparently have a really rare non-inherited version as I didn't have it at the time of the initial THR surgery 3 years ago.

      I have been trying to investigate, but there seems to be little knowledge out there probably due to Factor 7 being a 'one in a million' problem anyhow. That combined with my 'one in a million' hip malposition and subsequent ceramic fracture problem makes it doubly rare!

      I'll let you know if I or the doctors do come up with anything.

  • Posted

    can't help but just wanted to wish you the best. You've been so helpful to others on this site and i was so pleased that you'd got through your revision after the nightmare of your shattered implant. If anyone deserves a break, you do! Wishing you all the best.

    carola

    • Posted

      Yes agree, with your comment, Rocketman has helped a lots of us and given lots of good advice

      Ann

  • Posted

    i cant see how they would be related, cirrhosis is usually the result of years of damage either from fatty liver or alcohol or medication. Iam a nurse but not up to date on factor 7 deficency good luck

    • Posted

      I have seen reports of fish oil supplements affecting the blood results, and even damaging the liver really badly - I am also wondering if taking them has affected my liver function. I expect it'll all come clear with time.

      Factor 7 deficiency is extremely rare, so I am not surprised you are not up to date on that. It kicks off blood clotting after trauma, I am now finding when I have a wound, it is very slow to heal.

  • Posted

    Guys.

    For the last couple of years i have been waiting for LHR.

    The reason i have not had it done by now?

    Hemochromatosis.

    My liver was damaged, which in turn can have problems elsewhere.

    My surgeon was told by the professor from the liver clinic..you aint touching his hip until we have his liver under control. A whole host of issues why...

    However 3 years at clinic, blood letting, diet etc, im almost in a position where they agree it can be done.

    Hemochromatosis was only diagnosed in the late 20th century, so many early deaths due to this.

    People with this very rarely know they have it, until someone in the family catches sight by blood test, or through a post mortem.

    Hemochromatosis is a silent killer, can be fatal during surgery or post surgery. A patient with this condition, their blood is only good for the tropical medicine unit or the bin.

    Thx KAS

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