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Paroxetine works for me - panic disorder with agoraphobia, and depression. I was on it from 99-01, and then again from 2005 (and still on it). I've had minimal side effects, and I can leave the house, talk to people, get to work, and generally live a normal life.
I've come off of it twice (once in 2000, back on again six weeks later), and both times I found it caused no real problems - one day when I was a bit too dizzy to drive, but other than that fine. It's very important to drop down slowly, though.
I recently did a dose reduction to assess coming off of it again, but it didn't go well. Still, I am down from 30mg a day to 20mg a day. I'm fine with staying on this drug for as long as necessary.
I know there is a lot of noise against this medicine, and I do not dispute that some people have a hard time on the drug or coming off of it - I personally have not had this experience, and I'm one of the millions who have benefitted
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