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I've had symptoms that have gotten worse over about 10 years. The main symptoms are bone pain, thirst, urinary frequency, chronically loose skin and weak muscles from dehydration, indigestion, weight loss, and diarrhea.
I've taken lots of medication over the years, mostly for gastrointestinal issues, although none of the medications have really helped. Recently I started taking boron (between 3 and 9 mg per day) even though recent labs came back "negative" for hyperparathyroidism. In all my time taking prescription and non-prescription medications, the boron has helped me the most. It's helped me gain weight, reduced urinary frequency (from about 9 or 10 times per day to about 5), helped with thirst, and reduced bone pain.
Most recent lab tests are the following: PTH: 21 pg/ml, Vitamin D: 36 ng/ml, Calcium: 9.3 mg/dl (PTH and Vitamin D are low normal and calcium is normal). These suggest that I don't have hyperparathyroidism, and so my doctor hasn't continued investigating.
I also had an episode - the first so far - of getting extremely dehydrated from urinating too much, vomiting, nausea, extreme thirst, constipation, and dizziness. It lasted 3 days and I couldn't go to work. It kind of sounds like an episode of extremely high calcium, but when I got my labs they only showed dehydration, but not enough to be put on fluids at the hospital. I did go to the urgent care when I was able to move, so it's possible that I was in a better state.
I do remember having a 24 hour urine test which showed high calcium and phosphorus in the urine, and I had a few blood tests over the many years that have showed high calcium in the blood at various points.
I'm wondering if anyone has any suggestions of what to do next, or any other supplements I can try that would be helpful. The boron is extremely helpful. Taking calcium or Vitamin D increases urination and makes the dehydration much worse.
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