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Can anyone advise on how long leflunomide takes to start working? I'm currently on sulfazalazine and recently started leflunomide about 4 weeks ago. So far symptoms are still bad, particularly wrists and hands. I'm desperate for this to work, I've had ra for 6 years and feel is still not under property control. The constant pain and fatigue are getting me down and I can't plan anything as I never know how I'll be from one week to the next!! Thanx in advance.
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