Long lasting side effects from interactions between Bupropion and Levodopa usage?
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Hello, I have been prescribed Bupropion XL 150 mg for mental health issues and concentration. I took it for 2 months, starting from December 2021 to February 2022. Everything was fine until I incidentally ingested a supplement called Dopa Mucuna or Mucuna Pruriens, which contained 120 mg of L-Dopa. About exactly 30 minutes after intake of Dopa Mucuna, and while still on bupropion treatment, I experienced nausea and vomiting, tremors, dyskinesia, tics and twitching of muscles and body, inability to focus, loss of fine-motor skills, deterioration of hand-eye coordination and accuracies, a good example would be misclicking a lot with my computer mouse and making many typing mistakes on keyboard. After experiencing such side effects, I stopped bupropion, as for the supplement, it was a one-time thing, I took it many times before without bupropion administered and was fine, however, with bupropion, things happened. Anyways, it's been 2 months since the discontinuation of everything, and while symptoms improved, they never fully went away, I still get the occasional tics and twitches, these random fluctuating urge to move my body, sometimes it does it involuntarily, it gets better and mostly go quiet if I lie down in my bed, and also still worsen motor skills. I did some research, and both drugs are dopaminergic, and I might have experienced dopamine toxicity? I'm not sure what to do.
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